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Text
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URL Address
<a href="http://doi.org/10.7863/ultra.33.1.129" target="_blank" rel="noreferrer noopener">http://doi.org/10.7863/ultra.33.1.129</a>
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Pages
129-134
Issue
1
Volume
33
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Title
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Strain Elastography For Prediction Of Breast Cancer Tumor Grades
Publisher
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Journal of Ultrasound in Medicine
Date
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2014
2014-01
Subject
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Acoustics; agreement; breast; breast cancer; breast ultrasound; ductal carcinoma; elasticity; elastography; experience; grade; histologic grade; lesions; Nuclear Medicine & Medical Imaging; prognostic factors; Radiology; sonoelastography; sonography; strain; tumor; Ultrasound
Creator
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Grajo J R; Barr R G
Description
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Objectives-The purpose of this study was to determine whether the elasticity imaging/B-mode ratio on strain elastography can predict breast cancer tumor grades. Methods-A retrospective review of patients with breast lesions who underwent strain elastography and had a diagnosis of breast cancer by image-guided or surgical biopsy was performed. The axis of the maximum elastographic dimension was compared to the B-mode dimension to form an elasticity imaging/B-mode ratio. Lesions were categorized according to their pathologic type, including atypical ductal hyperplasia (ADH), mucinous or colloid cancer, ductal carcinoma in situ (DCIS), grade I invasive ductal carcinoma (MC), grade II IDC, grade III DC, invasive lobular carcinoma (ILC), and lymphoma. The mean elasticity imaging/B-mode ratio of each tumor type was calculated. The elasticity imaging/B-mode ratio of the tumor was compared to the tumor type by Kruskal-Wallis and Tukey-Kramer tests (lymphoma and ADH excluded because of small numbers). Results-Tumor grades included lymphoma (n = 3),.ADH (n = 2), mucinous cancer (n = 11), DCIS (n = 19), DC (grades I III; n = 200), and ILC (n = 31). The mean elasticity imaging/B-mode ratio varied with increasing tumor grade. Tumor grades could not have been selected at random from one population (P < .0001, chi(2) test). Invasive lobular carcinoma and grade III DC were statistically different from mucinous or colloid cancer, DCIS, and grade land II IDC. Conclusions-The elasticity imaging/B-mode ratio on strain elastography is related to the tumor grade.
Identifier
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<a href="http://doi.org/10.7863/ultra.33.1.129" target="_blank" rel="noreferrer noopener">10.7863/ultra.33.1.129</a>
Format
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Journal Article or Conference Abstract Publication
2014
Acoustics
agreement
Barr R G
breast
breast cancer
breast ultrasound
ductal carcinoma
Elasticity
elastography
experience
grade
Grajo J R
histologic grade
Journal Article or Conference Abstract Publication
Journal of Ultrasound in Medicine
lesions
Nuclear Medicine & Medical Imaging
prognostic factors
Radiology
sonoelastography
sonography
strain
Tumor
Ultrasound