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Text
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URL Address
<a href="http://doi.org/10.1080/08860220802213062" target="_blank" rel="noreferrer noopener">http://doi.org/10.1080/08860220802213062</a>
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Pages
759-762
Issue
7
Volume
30
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Title
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Fibrillary glomerulonephritis with hepatitis C viral infection and hypocomplementemia
Publisher
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Renal Failure
Date
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2008
2008
Subject
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deposits; entity; features; fibrillary glomerulonephritis; hepatitis C infection; hypocomplementemia; immunofluorescence; immunotactoid glomerulopathy; Urology & Nephrology
Creator
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Ray S; Rouse K; Appis A; Novak R; Haller N A
Description
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Fibrillary glomerulonephritis (FGN) is a relatively rare cause of renal disease, found in only 0.6-1.5% of native renal biopsies. The pathogenesis of FGN is not well described, and very few associations with disease processes other than hepatitis C virus (HCV) have been made. We describe a case that provides evidence in support of the FGN-HCV association, as well as introduces the association of FGN-HCV and hypocomplementemia. The case is a 53-year-old African-American female demonstrating a classical presentation of FGN complicated by a concomitant HCV infection. Treating an HCV infection with alpha-interferon has been shown to result in subsequent improvement in the nephrotic syndrome and renal function. However, this patient is unique in that she is complicated with hypocomplementemia, creating a complex treatment situation.
Identifier
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<a href="http://doi.org/10.1080/08860220802213062" target="_blank" rel="noreferrer noopener">10.1080/08860220802213062</a>
Format
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Journal Article
2008
Appis A
deposits
entity
features
fibrillary glomerulonephritis
Haller N A
hepatitis C infection
hypocomplementemia
immunofluorescence
immunotactoid glomerulopathy
Journal Article
Novak R
Ray S
Renal failure
Rouse K
Urology & Nephrology