1
40
2
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
290-299
Volume
833
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Amphiphilic Gels With Controlled Mesh Dimensions For Insulin Delivery
Publisher
An entity responsible for making the resource available
Polymer Gels: Fundamentals and Applications
Date
A point or period of time associated with an event in the lifecycle of the resource
2003
2003
Subject
The topic of the resource
drug release; islets; methacrylate)-1-polyisobutylene; networks; xenotransplantation
Creator
An entity primarily responsible for making the resource
Kennedy J P; Fenyvesi G; Na S; Keszler B; Rosenthal K S
Identifier
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n/a
Format
The file format, physical medium, or dimensions of the resource
Book Chapter
2003
Book Chapter
Drug Release
Fenyvesi G
islets
Kennedy J P
Keszler B
methacrylate)-1-polyisobutylene
Na S
networks
Polymer Gels: Fundamentals and Applications
Rosenthal K S
xenotransplantation
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
57-66
Volume
172
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Amphiphilic Membranes With Controlled Mesh Dimensions For Insulin Delivery
Publisher
An entity responsible for making the resource available
Macromolecular Symposia
Date
A point or period of time associated with an event in the lifecycle of the resource
2001
2001-06
Subject
The topic of the resource
immunosuppression; islets; networks; Polymer Science; porcine; release; xenotransplantation
Creator
An entity primarily responsible for making the resource
Kennedy J P; Fenyvesi G; Levy R P; Rosenthal K S
Description
An account of the resource
A series of amphiphilic networks (membranes), consisting of hydrophilic poly(N,N-dimethylacrylamide) (PDMAAM) main chains crosslinked by hydrophobic telechelic polyisobutylene di- and trimethacrylates (MA-PIB-MA or circle divide (PEB-MA)(3)) have been synthesized and used for the preparation of thin-walled tubules suitable for the immunoisolation of porcine islets. The molecular weight cut-off (MWCO) ranges, insulin and glucose diffusion coefficients and permeabilities of various membranes have been determined. The molecular weight of the PDMAAM moiety between two hydrophobic crosslinking points M-c,M-hydrophilic) controls permeability, which in turn can be controlled by synthesis conditions. The strengths and elongations of water-swollen membranes crosslinked with circle divide (PIB-MA)(3) are superior by a factor of about two to those prepared with MA-PIB-MA. Based on the values from these experiments, a well-defined membrane prepared with circle divide (PEB-MA)(3) was selected and used to encapsulate porcine islet cells. Gratifyingly, the encapsulated islet cells remain functional and viable, and cells within the tubule release insulin upon glucose challenge. These in vitro experiments are sufficiently promising to encourage us to continue our studies to develop a bioartificial pancreas.
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2001
Fenyvesi G
immunosuppression
islets
Journal Article or Conference Abstract Publication
Kennedy J P
Levy R P
Macromolecular Symposia
networks
Polymer Science
porcine
release
Rosenthal K S
xenotransplantation