1 40 1 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.1016/j.surg.2009.09.017" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.surg.2009.09.017</a> Rights Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). Pages 282-287 Issue 2 Volume 147 Search for Full-text Locate full-text within NEOMED Library's e-journal collections <p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Roux-en-Y gastric bypass reverses renal glomerular but not tubular abnormalities in excessively obese diabetics Publisher An entity responsible for making the resource available Surgery Date A point or period of time associated with an event in the lifecycle of the resource 2010 2010-02 Subject The topic of the resource bariatric-surgery; creatinine; disease; filtration-rate; follow-up; massive obesity; quality-of-life; risk-factors; serum cystatin-c; Surgery; young-adults Creator An entity primarily responsible for making the resource Saliba J; Kasim N R; Tamboli R A; Isbell J M; Marks P; Feurer I D; Ikizler A; Abumrad N N Description An account of the resource Background. Obesity and type 2 diabetes are associated with renal dysfunction, which improves after Roux-en-Y gastric bypass (RYGB). During a 12-month follow-up period, we studied prospectively the changes in glomerular and tubular functions that occurred in excessively obese diabetic and non diabetic subjects after, RYGB. Methods. The cohort included 35 patients, 54% of whom had type 2 diabetes. Glomerular filtration rate (GER) was estimated using creatinine clearance. Tubular function was studied by measuring the ratio of urinary cystatin C to urinary creatinine (UCC ratio). Results. Baseline renal parameters, anthropometric characteristics, and changes in body mass index after the surgical procedures were similar between the 2 cohorts. At 12 months after RYGB, creatinine clearance decreased 15% in diabetics (P = .02) and 21% in nondiabetics (P = .03). A change in GFR was seen earlier in the nondiabetics (-29% after 6 months; P = .003). The UCC ratio was increased at both 6- and 12-month follow-ups (P = .03 and .003, respectively) only in the diabetic group. Conclusion. GFR was improved at 12 months after RYGB, with nondiabetics showing a greater propensity score. Tubular function remained unchanged in. the nondiabetic subjects, but worsening occurred in the diabetic. subjects. These results underscore the importance of reversal of excessive obesity before the onset of frank diabetes. (Surgery 2010;147.-282-7.) Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1016/j.surg.2009.09.017" target="_blank" rel="noreferrer noopener">10.1016/j.surg.2009.09.017</a> Format The file format, physical medium, or dimensions of the resource Journal Article 2010 Abumrad N N bariatric-surgery Creatinine Disease Feurer I D filtration-rate Follow-up Ikizler A Isbell J M Journal Article Kasim N R Marks P massive obesity quality-of-life risk-factors Saliba J serum cystatin-c Surgery Tamboli R A young-adults