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Text
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URL Address
<a href="http://doi.org/10.1080/1120009x.2002.11782351" target="_blank" rel="noreferrer noopener">http://doi.org/10.1080/1120009x.2002.11782351</a>
Rights
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Pages
42-56
Volume
14
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Dublin Core
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Title
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Clinical and public health implications of macrolide-resistant Streptococcus pneumoniae
Publisher
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Journal of Chemotherapy
Date
A point or period of time associated with an event in the lifecycle of the resource
2002
2002-07
Subject
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Infectious Diseases; Pathology; united-states; Pharmacology & Pharmacy; in-vitro; Oncology; community-acquired pneumonia; macrolide resistance; streptococci; respiratory; pneumoniae; haemophilus-influenzae; moraxella-catarrhalis; tract infections; macrolides; otitis-media; group-a; erythromycin resistance; decreased susceptibility; initial antimicrobial therapy; pneumococcal resistance; S.; treatment failure
Creator
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Moellering R C; Consensus Working Grp
Description
An account of the resource
Macrolide resistance among Streptococcus pneumoniae is a growing global concern, although its specific impact on public health is not currently well defined. A Consensus Working Group was convened in March 2001 to address whether credible, scientific data substantiate macrolide resistance in S. pneumoniae as: (i) producing significant morbidity; (ii) creating attendant health and economic burdens; (iii) constituting a public health threat; and (iv) warranting intervention, including development of new antibiotics with efficacy against these strains. Despite the limitations of available clinical data, concern about the possibility of treatment failure with macrolides is being expressed in clinical practice and in formal treatment guidelines, threatening the important role of these agents in the treatment of respiratory tract infections. Further studies are required to monitor and control macrolide resistance and evaluate settings in which macrolide treatment failures are occurring, and new therapeutic interventions are needed.
Identifier
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<a href="http://doi.org/10.1080/1120009x.2002.11782351" target="_blank" rel="noreferrer noopener">10.1080/1120009x.2002.11782351</a>
Format
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Journal Article or Conference Abstract Publication
2002
Community-acquired pneumonia
Consensus Working Grp
decreased susceptibility
erythromycin resistance
group-a
haemophilus-influenzae
in-vitro
Infectious Diseases
initial antimicrobial therapy
Journal Article or Conference Abstract Publication
Journal of Chemotherapy
macrolide resistance
macrolides
Moellering R C
moraxella-catarrhalis
oncology
otitis-media
Pathology
Pharmacology & Pharmacy
pneumococcal resistance
pneumoniae
respiratory
S.
streptococci
tract infections
Treatment Failure
united-states