A Study Of Carbobenzoxy-d-phenylalanine-l-phenylalanine-glycine, An Inhibitor Of Membrane-fusion, In Phospholipid-bilayers With Multinuclear Magnetic-resonance
antiviral peptide; Biochemistry & Molecular Biology; Biophysics; h-2-nmr; mechanism; membrane fusion; multinuclear magnetic resonance; nmr; peptides; phase; replication; sendai virus fusion; vesicles
Dentino A R; Westerman P W; Yeagle P L
Biochimica Et Biophysica Acta-Biomembranes
1995
1995-05
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1016/0005-2736(95)80007-3" target="_blank" rel="noreferrer noopener">10.1016/0005-2736(95)80007-3</a>
Correlation of menstrual cycle at time of breast cancer surgery to disease-free and overall survival
carcinoma; General & Internal Medicine; killer cell-activity; mastectomy; operation; phase; premenopausal women; prognosis; receptor; stage; status; surgical cure
The timing of surgery during the menstrual cycle of premenopausal breast cancer patients was correlated with their disease-free survival (DFS) and overall survival (OS). The study included 150 premenopausal patients treated for breast cancer between 1977 and 1992. The data were analyzed using three different menstrual cycle phase categorization schemes: (1) days 0 to 6 and 21 to 32 vs 7 to 20; (2) days 0 to 2 and 19 to 32 vs 3 to 12; and (3) days 0 to 14 vs 14 to 32, Two different surgery dates used for analysis were biopsy date and definitive surgery date. There was no association of the timing of surgery with OS. Only one categorization scheme correlated with DFS (scheme No, 2), and this correlation was significant using either surgery or biopsy dates, Thus, premenopausal breast cancer patients who have biopsy and/or definitive surgery during their perimenstrual phase (days 0 to 2 or after day 13) of the menstrual cycle may have a longer DFS than patients operated on during their midcycle phase (days 3 to 13); however, this may not affect overall survival.
Vanek V W; Kadivar T F; Bourguet C C
Southern Medical Journal
1997
1997-08
Journal Article
<a href="http://doi.org/10.1097/00007611-199708000-00003" target="_blank" rel="noreferrer noopener">10.1097/00007611-199708000-00003</a>