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Text
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URL Address
<a href="http://doi.org/10.1185/030079904x3096" target="_blank" rel="noreferrer noopener">http://doi.org/10.1185/030079904x3096</a>
Rights
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Pages
1511-1521
Issue
10
Volume
20
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Managing patients with recurrent acute exacerbations of chronic bronchitis: a common clinical problem
Publisher
An entity responsible for making the resource available
Current Medical Research and Opinion
Date
A point or period of time associated with an event in the lifecycle of the resource
2004
2004-10
Subject
The topic of the resource
acute exacerbation; acute otitis media; airway inflammation; antimicrobial resistance; chronic bronchitis; chronic obstructive; community-acquired pneumonia; disease; empiric therapy; General & Internal Medicine; haemophilus-influenzae; moraxella-catarrhalis; obstructive-pulmonary-disease; pneumococcal; pneumonia; pulmonary; Research & Experimental Medicine; resistance; resistant streptococcus-pneumoniae; surveillance program
Creator
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Sethi S; File T M
Description
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Chronic obstructive pulmonary disease (COPD) affects 15 million people and is the fourth leading cause of death in the United States. It places a considerable burden on the healthcare system, with exacerbations contributing to a significant proportion of this burden. Patients with recurrent exacerbation, who experience more than 2 exacerbations per year, are especially difficult to manage. Several potential host, pathogen, and treatment factors can be identified that contribute to recurrent exacerbation. Patients with recurrent exacerbations are often exposed to frequent courses of antimicrobials. Therefore, antimicrobial resistance among common bacterial pathogens is likely to be prevalent in this group of patients, and further complicates therapy in this already difficult-to-treat patient population. In the management of patients with recurrent exacerbation, one goal should be to decrease the frequency of exacerbations, for which several strategies are suggested. In this article, we will review available literature identified through an extensive search of Medline and PubMed on the characteristics and approach to management of these difficult-to-treat patients. There is a substantial need for more research to understand the etiology and identify efficacious interventions to reduce the frequency of exacerbations of COPD.
Identifier
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<a href="http://doi.org/10.1185/030079904x3096" target="_blank" rel="noreferrer noopener">10.1185/030079904x3096</a>
Format
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Journal Article
2004
acute exacerbation
acute otitis media
airway inflammation
Antimicrobial resistance
chronic bronchitis
chronic obstructive
Community-acquired pneumonia
Current medical research and opinion
Disease
empiric therapy
File T M
General & Internal Medicine
haemophilus-influenzae
Journal Article
moraxella-catarrhalis
obstructive-pulmonary-disease
pneumococcal
Pneumonia
pulmonary
Research & Experimental Medicine
resistance
resistant streptococcus-pneumoniae
Sethi S
surveillance program