PALEOPATHOLOGY, ITS CHARACTER AND CONTRIBUTION TO UNDERSTANDING AND DISTINGUISHING AMONG RHEUMATOLOGIC DISEASES - PERSPECTIVES ON RHEUMATOID-ARTHRITIS AND SPONDYLOARTHROPATHY
ankylosis; defleshed bones; erosive arthritis; indians; new-world; nonhuman primates; paleopathology; polyarthritis; rheumatoid-arthritis; Rheumatology; spondyloarthropathy
Rothschild B M
Clinical and Experimental Rheumatology
1995
1995-09
Journal Article
n/a
CHARACTERIZATION OF GOUT IN A SKELETAL POPULATION-SAMPLE - PRESUMPTIVE DIAGNOSIS IN A MICRONESIAN POPULATION
Anthropology; chammorros; defleshed bones; differential diagnosis; disease; erosive arthritis; Evolutionary Biology; gout; guam; paleopathology; Pathology; polyarthritis; rheumatoid-arthritis; spondyloarthropathy
Characterization of the nature and skeletal distribution of gout was accomplished in a Chamoru (Chamorros) population with predilection to the disease. Uniform excavation by the gouty diathesis produces a punched-out appearance to these predominantly monarticular lesions. The lesion is distinct from that seen in rheumatoid arthritis, spondyloarthropathy, or infection. Reactive new bone formation in some gouty lesions also has an apparently unique, ivory-like discoloration (contrasted with the adjacent bone), which facilitates diagnosis. (C) 1995 Wiley-Liss, Inc.
Rothschild B M; Heathcote G M
American Journal of Physical Anthropology
1995
1995-12
Journal Article
<a href="http://doi.org/10.1002/ajpa.1330980411" target="_blank" rel="noreferrer noopener">10.1002/ajpa.1330980411</a>
Identification of childhood arthritis in archaeological material: Juvenile rheumatoid arthritis versus juvenile spondyloarthropathy
ankylosing spondylitis; Anthropology; bone erosion; criteria; defleshed bones; diagnosis; erosive arthritis; Evolutionary Biology; growth retardation; onset stills disease; Pathology; polyarthritis; pseudoarthrosis
The opportunity to examine the defleshed skeleton of an individual diagnosed in life (Hamann-Todd collection, individual 2036) afforded a unique opportunity to demonstrate the bone damage characteristic of at least one form of juvenile rheumatoid arthritis (JRA). Characteristics helpful for recognition of JRA in archaeological material include peripheral articular marginal and subchondral erosions, axial (e.g., zygapophyseal or sacroiliac) joint erosions, fusion of axial (cervical zygapophyseal) and/or peripheral joints, premature epiphyseal closure and/or ballooned epiphyses, growth retardation with underdeveloped (short and overtubulated) long bones, short mandibular rami with underdeveloped condyles and concomitant micrognathia, and demineralization (osteopenia). Distinguishing between JRA and juvenile spondyloarthropathy, however, is not always possible, as illustrated by this case. (C) 1995 Wiley-Liss, Inc.
Rothschild B M; Hershkovitz I; Bedford L; Latimer B; Dutour O; Rothschild C; Jellema L M
American Journal of Physical Anthropology
1997
1997-02
Journal Article
<a href="http://doi.org/10.1002/(sici)1096-8644(199702)102:2%3C249::aid-ajpa7%3E3.0.co;2-t" target="_blank" rel="noreferrer noopener">10.1002/(sici)1096-8644(199702)102:2%3C249::aid-ajpa7%3E3.0.co;2-t</a>
ARTHRITIS IN NEW-WORLD MONKEYS - OSTEOARTHRITIS, CALCIUM PYROPHOSPHATE DEPOSITION DISEASE, AND SPONDYLOARTHROPATHY
Alouatta; aotus; arthritis; ateles; calcium pyrophosphate deposition disease; callicebus; Callithrix; Cebus; chimpanzees; defleshed bones; erosive arthritis; lagothrix; osteoarthritis; pithecia; platyrrhini; polyarthritis; primate; primates; reactive; rhesus-monkeys; rheumatoid-arthritis; saguinus; saimiri; skeletal pathology; spondyloarthropathy; Zoology
Analyses of New World skeletal populations for the presence of erosions an other osseous alterations and their character, distribution, and radiologic appearance shows that osteoarthritis is predominantly a disease of animals raised in artificially constrained environments. Primary calcium pyrophosphate deposition disease (CPPD) was also found only in artificially constrained animals, although hyperparathyroidism (overproduction of parathyroid hormone) may have been responsible. CPPD was observed once as a secondary phenomenon, complicating another form of arthritis in free-ranging animals. Limited in occurrence to two genera, Alouatta and Cebus, the frequency of spondyloarthropathy was similar to that noted in humans and significantly lower than that observed in gorillas and chimpanzees. The many dichotomies of Cebus and Alouatta place them almost at opposite ends of the New World monkey spectrum, making a common susceptibility factor difficult to identify.
Rothschild B M; Woods R J
International Journal of Primatology
1993
1993-02
Journal Article
<a href="http://doi.org/10.1007/bf02196503" target="_blank" rel="noreferrer noopener">10.1007/bf02196503</a>
EROSIVE ARTHRITIS AND SPONDYLOARTHROPATHY IN OLD-WORLD PRIMATES
Anthropology; cercopithecus; colobus; disease; Evolutionary Biology; hla; hylobates; infection; macaca; papio; polyarthritis; presbytis; primate; psoriatic-arthritis; rhesus-monkey; rheumatoid-arthritis; skeletal pathology; theropithecus
Presence of spine and sacroiliac involvement and the nature and distribution of the erosive lesions allow definitive diagnosis of spondyloarthropathy. Thus, spondyloarthropathy was identified in Theropithecus, Papio, Cercopithecus, Macaca, Colobus, Presbytis, and Hylobates. Only monarticular erosive disease was present in prosimians, precluding a diagnosis of spondyloarthropathy for that group. The distribution of erosive disease and axial joint involvement in 1,349 non-prosimian Old World primates is quite characteristic of that noted in human psoriatic arthritis. While Reiter's syndrome must also be considered, the histologic appearance of skin lesions in Macaca is characteristic of psoriasis. Evidence of spondyloarthropathy abounds in the literature of primate skeletal disease. Environmentally based contagions may be important in the pathophysiology of spondyloarthropathy. The wide geographic distribution of the phenomena in monkeys suggests a "panendemic," with limited individual susceptibility (compared to that noted in gorillas and chimpanzees). Identical occurrence of erosive arthritis/spondyloarthropathy in free-ranging and artificially restrained animals suggests that spondyloarthropathy can validly be studied in artificially restrained populations. This perspective should allow application of human therapeutic approaches to and perhaps improve the quality of life for artificially restrained afflicted individuals.
Rothschild B M; Woods R J
American Journal of Physical Anthropology
1992
1992-07
Journal Article
<a href="http://doi.org/10.1002/ajpa.1330880310" target="_blank" rel="noreferrer noopener">10.1002/ajpa.1330880310</a>
SPONDYLOARTHROPATHY AS AN OLD-WORLD PHENOMENON
animal model of arthritis; apes; disease; erosive arthritis; hla; involvement; monkeys; polyarthritis; psoriatic-arthritis; rheumatoid-arthritis; Rheumatology; spondyloarthropathy
Rothschild B M; Woods R J
Seminars in Arthritis and Rheumatism
1992
1992-04
Journal Article
<a href="http://doi.org/10.1016/0049-0172(92)90024-8" target="_blank" rel="noreferrer noopener">10.1016/0049-0172(92)90024-8</a>
CHARACTER OF PRE-COLUMBIAN NORTH-AMERICAN SPONDYLOARTHROPATHY
ankylosing spondylitis; defleshed bones; enthesopathy; erosive arthritis; indians; joint fusion; new-world; paleopathology; polyarthritis; population; psoriatic-arthritis; reactive arthritis; rheumatoid-arthritis; Rheumatology; spondyloarthropathy
Shared characteristics and concurrent occurrence of rheumatoid arthritis (RA) and spondyloarthropathy in contemporary populations have compromised development of clear diagnostic criteria for distinguishing them. Although modern populations contain individuals with both RA and spondyloarthropathy, ancient populations often manifest only one. The presence of spondyloarthropathy as the sole erosive disease in selected ancient populations allows further clarification of its nature. The tendency towards pauciarticular, asymmetrical involvement, axial involvement and peripheral joint fusion in these populations clarifies diagnosis and distinguishes this phenomenon from RA. The significance of peripheral joint fusion appears to be unequivocally established on the basis of these findings.
Rothschild B M; Woods R J
Journal of Rheumatology
1992
1992-08
Journal Article
n/a