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Text
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URL Address
<a href="http://doi.org/10.1517/14656560903292649" target="_blank" rel="noreferrer noopener">http://doi.org/10.1517/14656560903292649</a>
Rights
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Pages
2759-2768
Issue
16
Volume
10
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Dublin Core
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Title
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Bimatoprost - a review
Publisher
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Expert Opinion on Pharmacotherapy
Date
A point or period of time associated with an event in the lifecycle of the resource
2009
2009-11
Subject
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acid; aqueous-humor; bimatoprost; clinical-trial; cost-effectiveness; elevated intraocular-pressure; fixed combination; free; glaucoma; human eyes; Intraocular pressure; ocular hypertension; open-angle glaucoma; Pharmacology & Pharmacy; prostaglandin; prostaglandin-ethanolamides; prostamide; prostamides
Creator
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Patil A J; Vajaranant T S; Edward D P
Description
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Bimatoprost is a synthetic prostamide analog that is efficacious in the treatment of open-angle glaucoma, ocular hypertension and other forms of glaucoma. it reduces intraocular pressure (IOP) by increasing uveoscleral and trabecular outflow. When used as a 0.03% topical preparation once daily, it demonstrates sustained lowering of IOP of 7 - 8 mmHg over a 24-h period. The drug has been found to be more effective than timolol. In some studies it has shown greater ability to lower IOP when compared with other prostaglandin analogs; whereas in others all three clinically used prostaglandin analogs were found to be equally effective. it shows good IOP reduction when used in combination with other glaucoma medications. A common side effect includes mild conjunctival hyperemia, which is generally reversible. Other side effects include periorbital pigmentation, discomfort, ocular surface hyperemia and skin changes. Pharmacoeconomic data indicate that bimatoprost is cost effective in the treatment of open-angle glaucoma.
Identifier
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<a href="http://doi.org/10.1517/14656560903292649" target="_blank" rel="noreferrer noopener">10.1517/14656560903292649</a>
Format
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Journal Article
2009
acid
aqueous-humor
bimatoprost
clinical-trial
cost-effectiveness
Edward D P
elevated intraocular-pressure
Expert Opinion on Pharmacotherapy
fixed combination
free
Glaucoma
human eyes
Intraocular Pressure
Journal Article
Ocular Hypertension
open-angle glaucoma
Patil A J
Pharmacology & Pharmacy
prostaglandin
prostaglandin-ethanolamides
prostamide
prostamides
Vajaranant T S