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Text
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URL Address
<a href="http://doi.org/10.1016/j.diagmicrobio.2010.01.005" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.diagmicrobio.2010.01.005</a>
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Pages
129-133
Issue
2
Volume
67
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Title
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Performance measure of urinary antigen in patients with Streptococcus pneumoniae bacteremia
Publisher
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Diagnostic Microbiology and Infectious Disease
Date
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2010
2010-06
Subject
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adults; assay binax; bacteremia; community-acquired pneumonia; diagnosis; etiologic diagnosis; infections; Infectious Diseases; management; Microbiology; pneumococcal pneumonia; rapid diagnosis; severity; sputum culture; Streptococcus pneumoniae; Urinary antigen
Creator
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Selickman J; Paxos M; File T M; Seltzer R; Bonilla H
Description
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The Streptococcus pneumoniae (SP) urinary antigen (UAg) test is a commonly used assay. The purpose cif this study was to evaluate the test's actual performance in the clinical setting and determine the effects of renal function, grade of bacteremia, and severity-of-illness scores on its outcome. Patients with pneumococcal bacteremia were retrospectively identified and stratified on the basis of glomerular filtration rates, number of positive blood cultures, and CURB-65 scores. Logistic regression was used to determine the effect that these 3 variables had on test outcomes. SP UAg testing was performed in 65 of 129 patients with pneumococcal bacteremia and was positive in 42 of 65 (64.5%). Impaired renal function was the only variable to have a significant effect on test outcome (P = 0.03). Test performance was less sensitive than prospective studies indicate. Patients with impaired renal function were significantly more likely to have positive UAg tests. (C) 2010 Elsevier Inc. All rights reserved.
Identifier
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<a href="http://doi.org/10.1016/j.diagmicrobio.2010.01.005" target="_blank" rel="noreferrer noopener">10.1016/j.diagmicrobio.2010.01.005</a>
Format
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Journal Article
2010
adults
assay binax
bacteremia
Bonilla H
Community-acquired pneumonia
Diagnosis
Diagnostic Microbiology and Infectious Disease
etiologic diagnosis
File T M
Infections
Infectious Diseases
Journal Article
Management
Microbiology
Paxos M
pneumococcal pneumonia
rapid diagnosis
Selickman J
Seltzer R
severity
sputum culture
Streptococcus pneumoniae
Urinary antigen