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Text
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URL Address
<a href="http://doi.org/10.1097/00007611-199708000-00003" target="_blank" rel="noreferrer noopener">http://doi.org/10.1097/00007611-199708000-00003</a>
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Pages
780-788
Issue
8
Volume
90
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Title
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Correlation of menstrual cycle at time of breast cancer surgery to disease-free and overall survival
Publisher
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Southern Medical Journal
Date
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1997
1997-08
Subject
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carcinoma; General & Internal Medicine; killer cell-activity; mastectomy; operation; phase; premenopausal women; prognosis; receptor; stage; status; surgical cure
Creator
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Vanek V W; Kadivar T F; Bourguet C C
Description
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The timing of surgery during the menstrual cycle of premenopausal breast cancer patients was correlated with their disease-free survival (DFS) and overall survival (OS). The study included 150 premenopausal patients treated for breast cancer between 1977 and 1992. The data were analyzed using three different menstrual cycle phase categorization schemes: (1) days 0 to 6 and 21 to 32 vs 7 to 20; (2) days 0 to 2 and 19 to 32 vs 3 to 12; and (3) days 0 to 14 vs 14 to 32, Two different surgery dates used for analysis were biopsy date and definitive surgery date. There was no association of the timing of surgery with OS. Only one categorization scheme correlated with DFS (scheme No, 2), and this correlation was significant using either surgery or biopsy dates, Thus, premenopausal breast cancer patients who have biopsy and/or definitive surgery during their perimenstrual phase (days 0 to 2 or after day 13) of the menstrual cycle may have a longer DFS than patients operated on during their midcycle phase (days 3 to 13); however, this may not affect overall survival.
Identifier
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<a href="http://doi.org/10.1097/00007611-199708000-00003" target="_blank" rel="noreferrer noopener">10.1097/00007611-199708000-00003</a>
Format
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Journal Article
1997
Bourguet C C
Carcinoma
General & Internal Medicine
Journal Article
Kadivar T F
killer cell-activity
Mastectomy
operation
phase
premenopausal women
Prognosis
Receptor
Southern medical journal
stage
status
surgical cure
Vanek V W