1
40
1
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
117-122
Issue
2
Volume
10
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
SYNOVITIS EQUIVALENT TO EROSIONS IN RHEUMATOID-ARTHRITIS - IMPLICATIONS OF SKELETAL ANALYSIS FOR THE CLINICAL MANAGEMENT OF CONTEMPORARY RHEUMATOID-ARTHRITIS
Publisher
An entity responsible for making the resource available
Clinical and Experimental Rheumatology
Date
A point or period of time associated with an event in the lifecycle of the resource
1992
1992-03
Subject
The topic of the resource
erosions; hand; joint disease; lesions; mortality; radiographs; radiologic assessment; rats; rheumatoid-arthritis; Rheumatology; skeletal radiology; synoviocytes; therapy; wrist
Creator
An entity primarily responsible for making the resource
Rothschild B M; Woods R J
Description
An account of the resource
Examination of a contemporary skeletal collection revealed a rheumatoid subgroup with parameters mirroring those of contemporary clinical populations. This rheumatoid population was also indistinguishable from contemporary (live) clinical populations, on the basis of the actual distribution of radiologically detectable erosions, thus validating its representativeness. Gross examination of these defleshed skeletons allowed assessment of the significance of erosive disease in rheumatoid arthritis. As anticipated, the frequency of visibly detectable erosions exceeded that detectable radiologically. The frequency of visibly detectable erosions, however, was indistinguishable from the frequency of synovitis in clinical populations. The excellent correlation of the gross and clinical distribution of disease suggests that some degree of erosive disease is integral to all lesions of rheumatoid arthritis and that only the relative insensitivity of radiologic techniques precludes universal recognition of those erosions. This work suggests that any therapeutic intervention which settles for only partial synovitis control will not prevent the progression of erosive disease; and perhaps explains the difficulty of demonstrating alterations in erosion progression in studies of disease modifying agents.
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article
1992
Clinical and experimental rheumatology
erosions
Hand
joint disease
Journal Article
lesions
Mortality
Radiographs
radiologic assessment
Rats
rheumatoid-arthritis
Rheumatology
Rothschild B M
skeletal radiology
synoviocytes
therapy
Woods R J
wrist