1
40
5
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0304-3940(93)90167-j" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0304-3940(93)90167-j</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
43-46
Issue
1
Volume
154
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
DEVELOPMENTAL ALTERATIONS IN N-METHYL-D-ASPARTATE STIMULATED H-3 NOREPINEPHRINE RELEASE IN RAT-BRAIN CORTEX AND HIPPOCAMPUS
Publisher
An entity responsible for making the resource available
Neuroscience Letters
Date
A point or period of time associated with an event in the lifecycle of the resource
1993
1993-05
Subject
The topic of the resource
hippocampus; cortex; development; receptors; Neurosciences & Neurology; system; ethanol; postnatal-development; cerebral-cortex; visual cortex; excitatory amino-acids; [h-3]norepinephrine release; n-methyl-d-aspartate; nmda-binding-sites; norepinephrine release; slice
Creator
An entity primarily responsible for making the resource
Brown L M
Description
An account of the resource
Developmental alterations in N-methyl-D-aspartate (NMDA)-stimulated [H-3]norepinephrine release from rat brain cortical and hippocampal slices were studied. NMDA (10-1000 muM) resulted in a concentration-dependent increase in [H-3]norepinephrine efflux; maximal responses (% released) in the cortex were: (1.53 +/- 0. 12, 3.68 +/- 0.20, 2.94 +/- 0.20, 4.60 +/- 0.28 and 5.28 +/- 0.33) and the hippocampal responses were: (1.90 +/- 0.18, 3.84 +/- 0.23, 3.60 +/- 0.28, 5.16 +/- 0.38 and 5.81 +/- 0.45) at varying postnatal ages (1, 7, 14, 21 and 90 days) respectively. Cortical tissue from 7-day-old pups exhibited a transient increase in maximal efflux and a decrease in EC50. These results indicated that developmental alterations in the NMDA receptor appear to be translated into differences in NMDA stimulated [H-3]norepinephrine release.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0304-3940(93)90167-j" target="_blank" rel="noreferrer noopener">10.1016/0304-3940(93)90167-j</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
[h-3]norepinephrine release
1993
Brown L M
cerebral-cortex
cortex
development
ETHANOL
excitatory amino-acids
Hippocampus
Journal Article or Conference Abstract Publication
N-Methyl-D-Aspartate
Neuroscience letters
Neurosciences & Neurology
nmda-binding-sites
norepinephrine release
postnatal-development
Receptors
slice
system
visual cortex
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0006-8993(93)90943-h" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0006-8993(93)90943-h</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
99-104
Issue
1
Volume
628
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Dublin Core
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Title
A name given to the resource
VISUAL DEPRIVATION DECREASES LONG-TERM POTENTIATION IN RAT VISUAL CORTICAL SLICES
Publisher
An entity responsible for making the resource available
Brain Research
Date
A point or period of time associated with an event in the lifecycle of the resource
1993
1993-11
Subject
The topic of the resource
cortex; rat; plasticity; depression; period; Neurosciences & Neurology; pathways; induction; long-term potentiation; organization; nmda receptors; evoked-potentials; visual cortex; critical; current source density; dark rearing; monocular deprivation; source density analysis
Creator
An entity primarily responsible for making the resource
Berry R L; Perkins A T; Teyler T J
Description
An account of the resource
A major finding in the visual plasticity literature is that visual deprivation is effective only during an early 'sensitive' period, which is lengthened by dark rearing. Unresolved is whether the visual cortex is in a normally plastic state prior to light stimulation. This cannot be addressed using paradigms employing light exposure to assess plasticity. Several developmental studies have investigated a plastic phenomenon termed long-term potentiation (LTP) in slices from cat (J. Neurophysiol., 59 (1988) 124-141) and rat (Brain Res., 439 (1988) 222-229) visual cortex. Susceptibility to the induction of LTP parallels the period of sensitivity to visual deprivation. This suggests that slices can be used to assay visual cortical plasticity, avoiding light exposure. In the present study, field potentials were recorded from slices of the primary visual cortices of dark-reared (DR) and control (CONT) Long Evans hooded rats (17 to 21 days). Field potential profiles recorded before and 90 min following tetanic electrical stimulation were subjected to current source density analysis, yielding extracellular current sink amplitudes. Tetanus resulted in LTP in both CONT and DR slices, but DR slices were significantly less potentiated. These results indicate that the primary visual cortex of DR animals is not fully plastic, indicating a role for light stimulation in inducing visual cortical plasticity.
Identifier
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<a href="http://doi.org/10.1016/0006-8993(93)90943-h" target="_blank" rel="noreferrer noopener">10.1016/0006-8993(93)90943-h</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
1993
Berry R L
Brain research
cortex
critical
current source density
dark rearing
Depression
evoked-potentials
induction
Journal Article or Conference Abstract Publication
Long-Term Potentiation
monocular deprivation
Neurosciences & Neurology
nmda receptors
organization
pathways
period
Perkins A T
plasticity
rat
source density analysis
Teyler T J
visual cortex
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1523/jneurosci.0047-12.2012" target="_blank" rel="noreferrer noopener">http://doi.org/10.1523/jneurosci.0047-12.2012</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
10470-10478
Issue
31
Volume
32
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Population-Wide Bias of Surround Suppression in Auditory Spatial Receptive Fields of the Owl's Midbrain
Publisher
An entity responsible for making the resource available
Journal of Neuroscience
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-08
Subject
The topic of the resource
barn owl; colliculus; difference; inferior; interaural time; macaque v1 neurons; motion-direction sensitivity; Neurosciences & Neurology; optic tectum; rat somatosensory cortex; superior colliculus; visual cortex; white-noise analysis
Creator
An entity primarily responsible for making the resource
Wang Y Y; Shanbhag S J; Fischer B J; Pena J L
Description
An account of the resource
The physical arrangement of receptive fields (RFs) within neural structures is important for local computations. Nonuniform distribution of tuning within populations of neurons can influence emergent tuning properties, causing bias in local processing. This issue was studied in the auditory system of barn owls. The owl's external nucleus of the inferior colliculus (ICx) contains a map of auditory space in which the frontal region is overrepresented. We measured spatiotemporal RFs of ICx neurons using spatial white noise. We found a population-wide bias in surround suppression such that suppression from frontal space was stronger. This asymmetry increased with laterality in spatial tuning. The bias could be explained by a model of lateral inhibition based on the overrepresentation of frontal space observed in ICx. The model predicted trends in surround suppression across ICx that matched the data. Thus, the uneven distribution of spatial tuning within the map could explain the topography of time-dependent tuning properties. This mechanism may have significant implications for the analysis of natural scenes by sensory systems.
Identifier
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<a href="http://doi.org/10.1523/jneurosci.0047-12.2012" target="_blank" rel="noreferrer noopener">10.1523/jneurosci.0047-12.2012</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2012
barn owl
colliculus
difference
Fischer B J
inferior
interaural time
Journal Article
Journal of Neuroscience
macaque v1 neurons
motion-direction sensitivity
Neurosciences & Neurology
optic tectum
Pena J L
rat somatosensory cortex
Shanbhag S J
superior colliculus
visual cortex
Wang Y Y
white-noise analysis
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0361-9230(91)90228-c" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0361-9230(91)90228-c</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
211-214
Issue
2
Volume
26
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Dublin Core
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Title
A name given to the resource
ONTOGENY OF THE DEPRESSANT ACTIVITY OF CARBACHOL ON SYNAPTIC ACTIVITY IN RAT VISUAL-CORTEX
Publisher
An entity responsible for making the resource available
Brain Research Bulletin
Date
A point or period of time associated with an event in the lifecycle of the resource
1991
1991-02
Subject
The topic of the resource
acetylcholine; area; brain; carbachol; hippocampus; muscarinic receptors; Neurosciences & Neurology; ontogeny; visual cortex
Creator
An entity primarily responsible for making the resource
Vaknin G; Teyler T J
Description
An account of the resource
We studied the ontogeny of muscarinic depression in the developing rat visual cortex using carbachol (a nonhydrolyzable cholinergic agonist) application to neocortical slices obtained from four postnatal age groups: 9-10 days, 15 days, 30-40 days and 18 months. Carbachol suppressed the evoked synaptic response of layers II-III to stimulation of layer II-III afferents. Atropine eliminated the carbachol effect, suggesting that it is mediated by muscarinic receptors. The results indicate a significant increase in muscarinic efficacy in the developing rat visual cortex.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0361-9230(91)90228-c" target="_blank" rel="noreferrer noopener">10.1016/0361-9230(91)90228-c</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
1991
Acetylcholine
area
Brain
Brain research bulletin
carbachol
Hippocampus
Journal Article
muscarinic receptors
Neurosciences & Neurology
ontogeny
Teyler T J
Vaknin G
visual cortex
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1152/jn.1998.79.1.334" target="_blank" rel="noreferrer noopener">http://doi.org/10.1152/jn.1998.79.1.334</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
334-341
Issue
1
Volume
79
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Title
A name given to the resource
Aging differentially alters forms of long-term potentiation in rat hippocampal area CA1
Publisher
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Journal of Neurophysiology
Date
A point or period of time associated with an event in the lifecycle of the resource
1998
1998-01
Subject
The topic of the resource
aged fischer-344 rats; alzheimers-disease; calcium channels; concentration-dependent manner; cortex; ltp induction; Neurosciences & Neurology; nmda receptors; Physiology; prefrontal; pyramidal neurons; synaptic transmission; visual cortex
Creator
An entity primarily responsible for making the resource
Shankar S; Teyler T J; Robbins N
Description
An account of the resource
Aging differentially alters forms of long-term potentiation in rat hippocampal area CAl. J. Neurophysiol. 79: 334-341, 1998. Long-term potentiation (LTP) of the Schaffer collateral/commissural inputs to CAI in the hippocampus was shown to consist of N-methyl-D-aspartate receptor (NMDAR) and voltage-dependent calcium channel (VDCC) dependent forms. In this study, the relative contributions of these two forms of LTP in in vitro hippocampal slices from young (2 mo) and old (24 mo) Fischer 344 rats were examined. Excitatory postsynaptic potentials (EPSP) were recorded extracellularly from stratum radiat-um before and after II tetanic stimulus consisting of four 200-Hz, 0.5-s trains given 5 s apart. Under control conditions, a compound LTP consisting of both forms was induced and was similar, in both time course and magnitude, in young and old animals. NMDAR-dependent LTP (nmdaLTP), isolated by the application of 10 mu M nifedipine (a voltage-dependent calcium channel blocker), was significantly reduced in magnitude in aged animals. The VDCC dependent form (vdccLTP), isolated by the application of 50 mu M D,L-2-amino-5-phosphonvalerate (APV), was significantly larger in aged animals. Although both LTP forms reached stable values 40-60 min posttetanus in young animals, in aged animals vdccLTP increased and nmdaLTP decreased during this time. In both young and old animals, the sum of the two isolated LTP forms approximated the magnitude of the compound LTP, and application of APV and nifedipine or genestein (a tyrosine kinase inhibitor) together blocked potentiation. These results suggest that aging causes a shift in synaptic plasticity from NMDAR-dependent mechanisms to VDCC-dependent mechanisms. The data are consistent with previous findings of increased L-type calcium current and decreased NMDAR number In aged CAI cells and may help explain age-related deficits in learning and memory.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1152/jn.1998.79.1.334" target="_blank" rel="noreferrer noopener">10.1152/jn.1998.79.1.334</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
1998
aged fischer-344 rats
alzheimers-disease
Calcium Channels
concentration-dependent manner
cortex
Journal Article
Journal of neurophysiology
ltp induction
Neurosciences & Neurology
nmda receptors
Physiology
prefrontal
pyramidal neurons
Robbins N
Shankar S
Synaptic Transmission
Teyler T J
visual cortex