Strain Elastography For Prediction Of Breast Cancer Tumor Grades

Title

Strain Elastography For Prediction Of Breast Cancer Tumor Grades

Creator

Grajo J R; Barr R G

Publisher

Journal of Ultrasound in Medicine

Date

2014
2014-01

Description

Objectives-The purpose of this study was to determine whether the elasticity imaging/B-mode ratio on strain elastography can predict breast cancer tumor grades. Methods-A retrospective review of patients with breast lesions who underwent strain elastography and had a diagnosis of breast cancer by image-guided or surgical biopsy was performed. The axis of the maximum elastographic dimension was compared to the B-mode dimension to form an elasticity imaging/B-mode ratio. Lesions were categorized according to their pathologic type, including atypical ductal hyperplasia (ADH), mucinous or colloid cancer, ductal carcinoma in situ (DCIS), grade I invasive ductal carcinoma (MC), grade II IDC, grade III DC, invasive lobular carcinoma (ILC), and lymphoma. The mean elasticity imaging/B-mode ratio of each tumor type was calculated. The elasticity imaging/B-mode ratio of the tumor was compared to the tumor type by Kruskal-Wallis and Tukey-Kramer tests (lymphoma and ADH excluded because of small numbers). Results-Tumor grades included lymphoma (n = 3),.ADH (n = 2), mucinous cancer (n = 11), DCIS (n = 19), DC (grades I III; n = 200), and ILC (n = 31). The mean elasticity imaging/B-mode ratio varied with increasing tumor grade. Tumor grades could not have been selected at random from one population (P < .0001, chi(2) test). Invasive lobular carcinoma and grade III DC were statistically different from mucinous or colloid cancer, DCIS, and grade land II IDC. Conclusions-The elasticity imaging/B-mode ratio on strain elastography is related to the tumor grade.

Subject

Acoustics; agreement; breast; breast cancer; breast ultrasound; ductal carcinoma; elasticity; elastography; experience; grade; histologic grade; lesions; Nuclear Medicine & Medical Imaging; prognostic factors; Radiology; sonoelastography; sonography; strain; tumor; Ultrasound

Format

Journal Article or Conference Abstract Publication

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Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

129-134

Issue

1

Volume

33

Citation

Grajo J R; Barr R G, “Strain Elastography For Prediction Of Breast Cancer Tumor Grades,” NEOMED Bibliography Database, accessed July 30, 2021, https://neomed.omeka.net/items/show/10003.

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