Effects Of Exercise On C-reactive Protein In Healthy Patients And In Patients With Heart Disease: A Meta-analysis

Title

Effects Of Exercise On C-reactive Protein In Healthy Patients And In Patients With Heart Disease: A Meta-analysis

Creator

Hammonds T L; Gathright E C; Goldstein C M; Penn M S; Hughes J W

Publisher

Heart & Lung

Date

2016
2016-05

Description

Decreases in circulating hsCRP have been associated with increased physical activity and exercise training, although the ability of exercise interventions to reduce hsCRP and which individuals benefit the most remains unclear. This meta-analysis evaluates the ability of exercise to reduce hsCRP levels in healthy individuals and in individuals with heart disease. A systematic review and meta-analysis was conducted that included exercise interventions trials from 1995 to 2012. Forty-three studies were included in the final analysis for a total of 3575 participants. Exercise interventions significantly reduced hsCRP (standardized mean difference -0.53 mg/L; 95% CI, -0.74 to -0.33). Results of sub-analysis revealed no significant difference in reductions in hsCRP between healthy adults and those with heart disease (p =.20). Heterogeneity between studies could not be attributed to age, gender, intervention length, intervention type, or inclusion of diet modification. Exercise interventions reduced hsCRP levels in adults irrespective of the presence of heart disease. (c) 2016 Elsevier Inc. All rights reserved.

Subject

Biological; body-composition; Cardiovascular System & Cardiology; cardiovascular-disease; Coronary disease; coronary-artery-disease; exercise; Heart disease; induced weight-loss; Inflammation; inflammatory markers; life-style intervention; marker c-reactive protein; Nursing; obese postmenopausal women; physical-activity; randomized controlled trial; Respiratory System; risk-factors; time

Format

Journal Article or Conference Abstract Publication

Search for Full-text

Users with a NEOMED Library login can search for full-text journal articles at the following url: https://libraryguides.neomed.edu/home

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

273-282

Issue

3

Volume

45

Citation

Hammonds T L; Gathright E C; Goldstein C M; Penn M S; Hughes J W, “Effects Of Exercise On C-reactive Protein In Healthy Patients And In Patients With Heart Disease: A Meta-analysis,” NEOMED Bibliography Database, accessed January 28, 2021, https://neomed.omeka.net/items/show/10064.

Social Bookmarking