Anomalous Phase Transition In Dipalmitoylphosphatidylethanolamine/palmitoylphosphatidylcholine/water System

Title

Anomalous Phase Transition In Dipalmitoylphosphatidylethanolamine/palmitoylphosphatidylcholine/water System

Creator

La Rosa C; Grasso D; Checchetti A; Golemme A; Chidichimo G; Westerman P

Publisher

Biophysical Chemistry

Date

1998
1998-01

Description

An anomalous phase transition with a marked rise in specific heat, the isobaric thermal expansion coefficient, and the compressibility coefficient at 62.5 degrees C for an equimolar mixture of 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE) and 1-palmitoyl-sn-glycero-3-phosphocholine (PLPC), in water (34 wt.%) has been shown by differential scanning calorimetry, scanning dilatometry and isothermal compressibility measurements. This transition occurs 15 degrees C above a first-order transition observed in the same system, P-31 and H-2 nuclear magnetic resonance results are consistent with the occurrence of 'defects' in the bilayer in the temperature range between the first and the anomalous phase transitions, It is proposed that conically, PLPC molecules prefer regions with high curvature in the defective bilayer, while DPPE molecules are mostly confined to the flat regions of the bilayers. (C) 1998 Elsevier Science B.V.

Subject

bilayer; Biochemistry & Molecular Biology; Biophysics; Chemistry; compressibility; DSC; lysolecithin; lysophosphatidylcholine; membrane; NMR; permeability; phase transition; phosphatidylcholine vesicles; phosphatidylethanolamine; phospholipid; phospholipid-vesicles; translocation; volumetric

Identifier

n/a

Format

Journal Article or Conference Abstract Publication

URL Address

n/a

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Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

11-20

Issue

1

Volume

70

Citation

La Rosa C; Grasso D; Checchetti A; Golemme A; Chidichimo G; Westerman P, “Anomalous Phase Transition In Dipalmitoylphosphatidylethanolamine/palmitoylphosphatidylcholine/water System,” NEOMED Bibliography Database, accessed March 5, 2021, https://neomed.omeka.net/items/show/10610.

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