Premature birth impacts bolus size and shape through nursing in infant pigs

Title

Premature birth impacts bolus size and shape through nursing in infant pigs

Creator

Mayerl Christopher J; Myrla Alexis M; Bond Laura E; Stricklen Bethany M; German Rebecca Z; Gould Francois D H

Publisher

Pediatric Research

Date

2019
2019-10-23

Description

BACKGROUND: The formation of a bolus of food is critical for proper feeding function, and there is substantial variation in the size and shape of a bolus prior to a swallow. Preterm infants exhibit decreased abilities to acquire and process food, but how that relates to their bolus size and shape is unknown. Here, we test two hypotheses: (1) that bolus size and shape will differ between term and preterm infants, and (2) bolus size and shape will change longitudinally through development in both term and preterm infants. METHODS: To test these hypotheses, we measured bolus size and shape in preterm and term infant pigs longitudinally through nursing using high-speed videofluoroscopy. RESULTS: Preterm infant pigs swallowed smaller volumes of milk. Although term infants increased the amount of milk per swallow as they aged, preterm infants did not. These changes in bolus volume were also correlated with changes in bolus shape; larger boluses became more elongate as they better filled the available anatomical space of the valleculae. CONCLUSIONS: These results suggest that preterm birth reduces the ability of preterm pigs to increase bolus size as they grow, affecting development in this fragile population. These results highlight that studies on term infant feeding may not translate to preterm infants.

Identifier

PMID: 31645052

Format

Journal Article

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Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

ISSN

1530-0447

Citation

Mayerl Christopher J; Myrla Alexis M; Bond Laura E; Stricklen Bethany M; German Rebecca Z; Gould Francois D H, “Premature birth impacts bolus size and shape through nursing in infant pigs,” NEOMED Bibliography Database, accessed June 19, 2021, https://neomed.omeka.net/items/show/10830.

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