Inhibition of Histone H3K27 Acetylation Orchestrates Interleukin-9-Mediated and Plays an Anti-Inflammatory Role in Cisplatin-Induced Acute Kidney Injury.

Title

Inhibition of Histone H3K27 Acetylation Orchestrates Interleukin-9-Mediated and Plays an Anti-Inflammatory Role in Cisplatin-Induced Acute Kidney Injury.

Creator

Jiang Wenjuan; Yuan Xinrong; Zhu Hong; He Changsheng; Ge Caiqiong; Tang Qing; Xu Chuanting; Hu Bingfeng; Huang Cheng; Ma Taotao

Publisher

Frontiers in immunology

Date

2020
1905-07

Description

Nephrotoxicity is a major side effect of cisplatin (CP)- and platinum-related chemotherapy, and inflammation contributes to disease pathogenesis. Interleukin-9 (IL-9) is a pleiotropic cytokine associated with inflammation. Here, we investigated the key role of IL-9 as a regulator of protective mechanisms in

Subject

acid; acute kidney injury; apoptosis; bmp-7; cisplatin; expression; H3K27Ac; il-9; inflammation; interleukin-9; macrophage; receptor; renal inflammation; tubular epithelial-cells

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Format

journalArticle

Search for Full-text

Users with a NEOMED Library login can search for full-text journal articles at the following url: https://libraryguides.neomed.edu/home

Pages

231

Volume

11

ISSN

1664-3224 1664-3224

NEOMED College

NEOMED College of Pharmacy

NEOMED Department

NEOMED Postdoc Publications

Update Year & Number

June 2020 Update I

Citation

Jiang Wenjuan; Yuan Xinrong; Zhu Hong; He Changsheng; Ge Caiqiong; Tang Qing; Xu Chuanting; Hu Bingfeng; Huang Cheng; Ma Taotao, “Inhibition of Histone H3K27 Acetylation Orchestrates Interleukin-9-Mediated and Plays an Anti-Inflammatory Role in Cisplatin-Induced Acute Kidney Injury.,” NEOMED Bibliography Database, accessed January 21, 2021, https://neomed.omeka.net/items/show/11009.

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