Ultrasound liver elastography beyond liver fibrosis assessment

Title

Ultrasound liver elastography beyond liver fibrosis assessment

Creator

Ferraioli G; Barr RG

Publisher

World Journal of Gastroenterology

Date

2020
2020-06-28

Description

Several guidelines have indicated that liver stiffness (LS) assessed by means of shear wave elastography (SWE) can safely replace liver biopsy in several clinical scenarios, particularly in patients with chronic viral hepatitis. However, an increase of LS may be due to some other clinical conditions not related to fibrosis, such as liver inflammation, acute hepatitis, obstructive cholestasis, liver congestion, infiltrative liver diseases. This review analyzes the role that SWE can play in cases of liver congestion due to right-sided heart failure, congenital heart diseases or valvular diseases. In patients with heart failure LS seems directly influenced by central venous pressure and can be used as a prognostic marker to predict cardiac events. The potential role of LS in evaluating liver disease beyond the stage of liver fibrosis has been investigated also in the hepatic sinusoidal obstruction syndrome (SOS) and in the Budd-Chiari syndrome. In the hepatic SOS, an increase of LS is observed some days before the clinical manifestations; therefore, it could allow an early diagnosis to timely start an effective treatment. Moreover, it has been reported that patients that were successfully treated showed a LS decrease, that reached pre-transplantation value within two to four weeks. It has been reported that, in patients with Budd-Chiari syndrome, LS values can be used to monitor short and long-term outcome after angioplasty.

Subject

Heart failure; children; guidelines; Liver stiffness; Shear wave elastography; transient elastography; consensus; portal-hypertension; heart; Budd Chiari syndrome; central venous-pressure; congestion; fontan circulation; Fontan circulation; Hepatic sinusoidal obstruction syndrome; Liver congestion; stiffness measurements; Valvular diseases; Liver congestion

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Format

journalArticle

Search for Full-text

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Pages

3413-3420

Issue

24

Volume

26

ISSN

1007-9327

NEOMED College

NEOMED College of Medicine

NEOMED Department

Department of Radiology

Update Year & Number

August 2020 List

Affiliated Hospital

Mercy Health St Elizabeth Boardman Hospital

Citation

Ferraioli G; Barr RG, “Ultrasound liver elastography beyond liver fibrosis assessment,” NEOMED Bibliography Database, accessed January 19, 2021, https://neomed.omeka.net/items/show/11216.

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