Development of acute kidney injury following pediatric cardiac surgery.

Title

Development of acute kidney injury following pediatric cardiac surgery.

Creator

Sharma A; Chakraborty R; Sharma K; Sethi SK; Raina R

Publisher

Kidney Research and Clinical Practice

Date

2020
2020-08-10

Description

Acute kidney injury (AKI) in the pediatric population is a relatively common phenomenon. Specifically, AKI has been found in increasing numbers within the pediatric population following cardiac surgery, with up to 43% of pediatric patients developing AKI post-cardiac surgery. However, recent advances have allowed for the identification of risk factors. These can be divided into preoperative, intraoperative, and postoperative factors. Although the majority of pediatric patients developing AKI after cardiac surgery completely recover, this condition is associated with worse outcomes. These include fluid overload and increased mortality and result in longer hospital and intensive care unit stays. Detecting the presence of AKI has advanced; use of relatively novel biomarkers, including neutrophil gelatinase associated lipocalin, has shown promise in detecting more subtle changes in kidney function when compared to conventional methods. While a single, superior treatment has not been elucidated yet, novel functions of medications, including fenoldopam, theophylline and aminophylline, have been shown to have better outcomes for these patients. With the recent advances in identification of risk factors, outcomes, diagnosis, and management, the medical community can further explain the complexities of AKI in the pediatric population post-cardiac surgery.

Subject

Pediatrics; Acute kidney injury; Nephrology; Thoracic surgery

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Format

journalArticle

Search for Full-text

Users with a NEOMED Library login can search for full-text journal articles at the following url: https://libraryguides.neomed.edu/home

ISSN

2211-9132

NEOMED College

NEOMED College of Medicine

NEOMED Department

NEOMED Student Publications

Update Year & Number

August 2020 List

Citation

Sharma A; Chakraborty R; Sharma K; Sethi SK; Raina R, “Development of acute kidney injury following pediatric cardiac surgery.,” NEOMED Bibliography Database, accessed January 20, 2021, https://neomed.omeka.net/items/show/11231.

Social Bookmarking