Development of acute kidney injury following pediatric cardiac surgery.
Title
Development of acute kidney injury following pediatric cardiac surgery.
Creator
Sharma A; Chakraborty R; Sharma K; Sethi SK; Raina R
Publisher
Kidney Research and Clinical Practice
Date
2020
2020-08-10
Description
Acute kidney injury (AKI) in the pediatric population is a relatively common phenomenon. Specifically, AKI has been found in increasing numbers within the pediatric population following cardiac surgery, with up to 43% of pediatric patients developing AKI post-cardiac surgery. However, recent advances have allowed for the identification of risk factors. These can be divided into preoperative, intraoperative, and postoperative factors. Although the majority of pediatric patients developing AKI after cardiac surgery completely recover, this condition is associated with worse outcomes. These include fluid overload and increased mortality and result in longer hospital and intensive care unit stays. Detecting the presence of AKI has advanced; use of relatively novel biomarkers, including neutrophil gelatinase associated lipocalin, has shown promise in detecting more subtle changes in kidney function when compared to conventional methods. While a single, superior treatment has not been elucidated yet, novel functions of medications, including fenoldopam, theophylline and aminophylline, have been shown to have better outcomes for these patients. With the recent advances in identification of risk factors, outcomes, diagnosis, and management, the medical community can further explain the complexities of AKI in the pediatric population post-cardiac surgery.
Subject
Pediatrics; Acute kidney injury; Nephrology; Thoracic surgery
Identifier
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Format
journalArticle
URL Address
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ISSN
2211-9132
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NEOMED College of Medicine
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Update Year & Number
August 2020 List
Citation
Sharma A; Chakraborty R; Sharma K; Sethi SK; Raina R, “Development of acute kidney injury following pediatric cardiac surgery.,” NEOMED Bibliography Database, accessed April 25, 2024, https://neomed.omeka.net/items/show/11231.