Evaluation of anticoagulation practice with new-onset atrial fibrillation in patients with sepsis and septic shock in medical intensive care unit: A retrospective observational cohort study.

Title

Evaluation of anticoagulation practice with new-onset atrial fibrillation in patients with sepsis and septic shock in medical intensive care unit: A retrospective observational cohort study.

Creator

Arunachalam K;Kalyan SA;Jha K;Thakur L;Pond K

Publisher

Cureus

Date

2020
2020-08-25

Description

Objective To investigate the anticoagulation practice in patients presenting with new-onset atrial fibrillation (NOAF) during sepsis and septic shock with one-year follow-up since discharge and to evaluate factors associated with the development of NOAF. Methods A retrospective observational cohort study was conducted using chart review in patients diagnosed with sepsis and septic shock.  Results There was a total of 1132 patients diagnosed with sepsis and septic shock over a one-year period. Thirty-two patients were found to have NOAF in the setting of sepsis. Of this, eight (25%) patients were anticoagulated with warfarin and 14 (44%) patients were not anticoagulated during discharge. At one-year follow-up post-discharge, nine (29%) patients continued on warfarin and 16 (52%) patients remained not anticoagulated. Conclusion We found that the majority of patients who developed NOAF did not get anticoagulated at the time of discharge. A similar trend followed after one year of follow-up. Since proper treatment guidelines are not in place, these patients are at high risk for recurrent atrial fibrillation, stroke, transient ischemic attack, and death. (Copyright © 2020, Arunachalam et al.)

Subject

severe sepsis; septic shock; atrial fibrillation; critical care; anticoagulation

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Format

journalArticle

Search for Full-text

Users with a NEOMED Library login can search for full-text journal articles at the following url: https://libraryguides.neomed.edu/home

Pages

e10026

Issue

8

Volume

12

ISSN

2168-8184

NEOMED College

NEOMED College of Medicine

NEOMED Department

Department of Internal Medicine

Update Year & Number

September 2020 List

Citation

Arunachalam K;Kalyan SA;Jha K;Thakur L;Pond K, “Evaluation of anticoagulation practice with new-onset atrial fibrillation in patients with sepsis and septic shock in medical intensive care unit: A retrospective observational cohort study.,” NEOMED Bibliography Database, accessed January 21, 2021, https://neomed.omeka.net/items/show/11262.

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