Updated guidance on the management of covid-19: From an American Thoracic Society/European Respiratory Society coordinated international task force (29 july 2020).

Updated guidance on the management of covid-19: From an American Thoracic Society/European Respiratory Society coordinated international task force (29 july 2020).

Bai C;Chotirmall SH;Rello J;Alba GA;Ginns LC;Krishnan JA;Rogers R;Bendstrup E;Burgel P;Chalmers JD;Chua A;Crothers KA;Duggal A;Kim YW;Laffey John G;Luna CM;Niederman MS;Raghu G;Ramirez JA;Riera J;Roca O;Tamae-Kakazu M;Torres A;Watkins RR;Barrecheguren M;Belliato M;Chami HA;Chen R;Cortes-Puentes GA;Delacruz C;Hayes MM;Heunks LMA;Holets SR;Hough CL;Jagpal S;Jeon K;Johkoh T;Lee MM;Liebler J;McElvaney GN;Moskowitz A;Oeckler RA;Ojanguren I;O'Regan A;Pletz MW;Rhee CK;Schultz MJ;Storti E;Strange C;Thomson CC;Torriani FJ;Wang X;Wuyts W;Xu T;Yang D;Zhang Z;Wilson KC

European Respiratory Review

2020

2020-10-05

Background: Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome-coronavirus-2. Consensus suggestions can standardise care, thereby improving outcomes and facilitating future research.; Methods: An International Task Force was composed and agreement regarding courses of action was measured using the Convergence of Opinion on Recommendations and Evidence (CORE) process. 70% agreement was necessary to make a consensus suggestion.; Results: The Task Force made consensus suggestions to treat patients with acute COVID-19 pneumonia with remdesivir and dexamethasone but suggested against hydroxychloroquine except in the context of a clinical trial; these are revisions of prior suggestions resulting from the interim publication of several randomised trials. It also suggested that COVID-19 patients with a venous thromboembolic event be treated with therapeutic anticoagulant therapy for 3 months. The Task Force was unable to reach sufficient agreement to yield consensus suggestions for the post-hospital care of COVID-19 survivors. The Task Force fell one vote shy of suggesting routine screening for depression, anxiety and post-traumatic stress disorder.; Conclusions: The Task Force addressed questions related to pharmacotherapy in patients with COVID-19 and the post-hospital care of survivors, yielding several consensus suggestions. Management options for which there is insufficient agreement to formulate a suggestion represent research priorities. (Copyright ©ERS 2020.)

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journalArticle

157

29

1600-0617

NEOMED College of Medicine

Department of Internal Medicine

September 2020 List