Evaluation of the FUSION-X-US-II prototype to combine automated breast ultrasound and tomosynthesis

Title

Evaluation of the FUSION-X-US-II prototype to combine automated breast ultrasound and tomosynthesis

Creator

Schaefgen B; Juskic M; Radicke M; Hertel M; Barr R; Pfob A; Togawa R; Nees J; von Au A; Fastner S; Harcos A; Gomez C; Stieber A; Riedel F; Hennigs A; Sohn C; Heil J; Golatta M

Publisher

European Radiology

Description

Objective The FUSION-X-US-II prototype was developed to combine 3D automated breast ultrasound (ABUS) and digital breast tomosynthesis in a single device. We evaluated the performance of ABUS and tomosynthesis in a single examination in a clinical setting. Methods In this prospective feasibility study, digital breast tomosynthesis and ABUS were performed using the FUSION-X-US-II prototype without any change of the breast position in patients referred for clarification of breast lesions with an indication for tomosynthesis. The tomosynthesis and ABUS images of the prototype were interpreted independently from the clinical standard by a breast diagnostics specialist. Any detected lesion was classified using BI-RADS (R) scores, and results of the standard clinical routine workup (gold standard) were compared to the result of the separate evaluation of the prototype images. Image quality was rated subjectively and coverage of the breast was measured. Results One hundred one patients received both ABUS and tomosynthesis using the prototype. The duration of the additional ABUS acquisition was 40 to 60 s. Breast coverage by ABUS was approximately 80.0%. ABUS image quality was rated as diagnostically useful in 86 of 101 cases (85.1%). Thirty-three of 34 malignant breast lesions (97.1%) were identified using the prototype. Conclusion The FUSION-X-US-II prototype allows a fast ABUS scan in combination with digital breast tomosynthesis in a single device integrated in the clinical workflow. Malignant breast lesions can be localized accurately with direct correlation of ABUS and tomosynthesis images. The FUSION system shows the potential to improve breast cancer screening in the future after further technical improvements.

Subject

Imaging; Ultrasonography; Mammography; mammary; Early detection of cancer; Multimodal imaging; three-dimensional

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Format

journalArticle

Search for Full-text

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ISSN

0938-7994

NEOMED College

NEOMED College of Medicine

NEOMED Department

Department of Radiology

Update Year & Number

January 2021 List

Affiliated Hospital

Mercy Health St. Elizabeth Boardman Hospital

Citation

Schaefgen B; Juskic M; Radicke M; Hertel M; Barr R; Pfob A; Togawa R; Nees J; von Au A; Fastner S; Harcos A; Gomez C; Stieber A; Riedel F; Hennigs A; Sohn C; Heil J; Golatta M, “Evaluation of the FUSION-X-US-II prototype to combine automated breast ultrasound and tomosynthesis,” NEOMED Bibliography Database, accessed May 16, 2021, https://neomed.omeka.net/items/show/11518.

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