Primary Squamous Cell Carcinoma of the Thyroid: A Case Report and Literature Review About a Rare Entity

Title

Primary Squamous Cell Carcinoma of the Thyroid: A Case Report and Literature Review About a Rare Entity

Creator

Soror NN; Shah P; Hemrock L; Bennett R

Publisher

Cureus

Date

2021
2021-05-11

Description

Primary squamous cell carcinoma of the thyroid (PSCCT) is a rare and aggressive neoplasm that accounts for less than 1% of all thyroid malignancies. Its incidence is higher in females in their fifth and sixth decades of life. The pathophysiology of PSCCT is still a subject of debate as squamous cells are generally absent in the thyroid gland under normal physiologic conditions. Immunohistochemistry is important for reaching a definite diagnosis as it helps to differentiate PSCCT from metastases from other primary sites. Clinically, PSCCT usually presents as a rapidly enlarging anterior neck mass. Surgical resection is the mainstay of treatment despite the lack of any standard guidelines for the same given the rarity of the disease. Adjuvant chemotherapy, radiotherapy, and targeted therapy continue to be of unclear benefit. We report a case of PSSCT in a male patient who presented with a rapidly enlarging neck mass.

Subject

squamous cell carcinoma; squamous cell carcinoma (scc); thryroid; thyroid cancer

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Format

journalArticle

Search for Full-text

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Issue

5

Volume

13

NEOMED College

NEOMED College of Medicine

NEOMED Department

Department of Internal Medicine

Update Year & Number

June 2021 List

Citation

Soror NN; Shah P; Hemrock L; Bennett R, “Primary Squamous Cell Carcinoma of the Thyroid: A Case Report and Literature Review About a Rare Entity,” NEOMED Bibliography Database, accessed June 29, 2022, https://neomed.omeka.net/items/show/11715.

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