Acute Tramadol Ingestion With Transient Acute Kidney Injury in an Adolescent Female.

Acute Tramadol Ingestion With Transient Acute Kidney Injury in an Adolescent Female.

Mike TB; DeVault H; Blackford MG

Journal Of Pediatric Pharmacology & Therapeutics

2021

2021-05

Renal toxicity has been described with tramadol overdoses; however, it is typically associated with rhabdomyolysis, multiorgan failure and/or mortality. Our patient was a 16-year-old female who was evaluated following an intentional tramadol ingestion, estimated 27.8 to 37 mg/kg, and had a seizure prior to arriving at our health care facility. Her symptoms were consistent with a tramadol ingestion; however, she developed transient acute renal impairment (peak serum creatinine, 4.04 mg/dL), which improved over 6 days with minimal intervention. No other causes were identified to explain her acute renal impairment thus it was attributed to the tramadol overdose. Providers should be aware that transient acute renal impairment could occur with an intentional tramadol ingestion and may not require aggressive intervention. [ABSTRACT FROM AUTHOR]

acute kidney injury; DRUG side effects; adolescent; tramadol; ACUTE kidney failure; case report; adverse drug effect; analgesics; drug overdose; RHABDOMYOLYSIS; STRIATED muscle necrosis; TRAMADOL

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journalArticle

411-413

4

26

15516776

NEOMED College of Medicine

Department of Pediatrics

June 2021 List