Hypermagnesaemia causing mesenteric ischaemia and small bowel infarction
Title
Hypermagnesaemia causing mesenteric ischaemia and small bowel infarction
Creator
Hubbard G; Nerad R; Wojtasik L
Publisher
BMJ Case Reports
Date
2021
Description
We present a case of mesenteric ischaemia caused by hypermagnesaemia after ingestion of a large oral dose of magnesium citrate, which resulted in smooth muscle relaxation, hypotension and bowel infarction. The patient had a history of chronic bowel dysmotility and renal impairment. On operative exploration, the bowel was noted to have a distinct pattern of ischaemia along its antimesenteric border. Small bowel resection was performed, and the patient was left in discontinuity, with definitive repair and anastomosis performed 24 hours later. The patient's magnesium level was 8.39 mg/dL, which was treated with intermittent haemodialysis and eventually normalised over several sessions. Our patient recovered and was discharged after a month-long hospitalisation. She returned shortly after with respiratory failure and died. On review of the literature, we identified similar cases and present a pathophysiological mechanism of hypermagnesaemia causing mesenteric ischaemia, consistent between our cases and those already reported.
Subject
fluid electrolyte and acid-base disturbances; gastrointestinal surgery; general surgery; renal medicine; surgery
Identifier
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Format
journalArticle
URL Address
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NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of General Surgery
Citation
Hubbard G; Nerad R; Wojtasik L, “Hypermagnesaemia causing mesenteric ischaemia and small bowel infarction,” NEOMED Bibliography Database, accessed March 28, 2024, https://neomed.omeka.net/items/show/11755.