A Novel Exercise Testing Algorithm to Diagnose Mitochondrial Myopathy.

Title

A Novel Exercise Testing Algorithm to Diagnose Mitochondrial Myopathy.

Creator

Bhatia Rajeev;Cohen BH;McNinch N

Publisher

Muscle & Nerve

Date

2021
2021-02-03

Description

We performed cycle ergometer maximal exercise testing on definite and suspected mitochondrial myopathy subjects (MM-D and MM-S) and their age- and sex-matched controls. OUES was corrected for body surface area (OUES/BSA) to eliminate the effect of body size.

Subject

Oxygen uptake efficiency slope (OUES) is a noninvasive cardiopulmonary exercise testing (CPET) measurement based on oxygen uptake (V˙O2) and minute ventilation (V˙E) and is a marker of the efficiency of oxygen utilization by the body. However, it has not been studied in mitochondrial disorders. We explored noninvasive CPET parameters, including OUES, as a way to reliably diagnose mitochondrial myopathy.

Identifier

10.1002/mus.27191

Format

Journal Article

URL Address

https://doi.org/10.1002/mus.27191

Pages

715-723

Issue

5

Volume

63

NEOMED College

NEOMED College of Medicine

NEOMED Department

Department of Pediatrics, Department of integrative Medical Science

Citation

Bhatia Rajeev;Cohen BH;McNinch N, “A Novel Exercise Testing Algorithm to Diagnose Mitochondrial Myopathy.,” NEOMED Bibliography Database, accessed January 20, 2025, https://neomed.omeka.net/items/show/11782.