Distribution and origin of corticotropin-releasing factor-immunoreactive axons in the female rat lumbosacral spinal cord.

Title

Distribution and origin of corticotropin-releasing factor-immunoreactive axons in the female rat lumbosacral spinal cord.

Creator

Puder B A; Papka R E

Publisher

Journal of neuroscience research

Date

2001
2001-12

Description

Corticotropin-releasing factor (CRF) is a neuropeptide traditionally known for its hormonal role in the hypothalamic/pituitary/adrenal stress axis. However, CRF has been reported in axons in sites that may be considered outside of the direct stress axis, e.g., in axons in the lumbosacral spinal cord associated with the micturition response. Whether any of these CRF-immunoreactive axons interacts with uterine-related preganglionic autonomic neurons or projection neurons in the lumbosacral spinal cord is unknown. Thus, immunohistochemistry and retrograde tracing were employed to determine the presence, distribution, and origin of

Subject

Animals; Axons/*metabolism/ultrastructure; Brain/cytology/*metabolism; Corticotropin-Releasing Hormone/*metabolism; Efferent Pathways/cytology/*metabolism; Female; Fluorescent Dyes; Herpesvirus 1; Immunohistochemistry; Lumbar Vertebrae; NADPH Dehydrogenase/metabolism; Nitrergic Neurons/cytology/metabolism; Parasympathetic Nervous System/cytology/*metabolism; Paraventricular Hypothalamic Nucleus/cytology/metabolism; Pons/cytology/metabolism; Pregnancy; Presynaptic Terminals/metabolism/ultrastructure; Rats; Reproduction/physiology; Sacrum; Spinal Cord/cytology/*metabolism; Sprague-Dawley; Suid; Uterus/*innervation

Identifier

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

1217–1225

Issue

6

Volume

66

Citation

Puder B A; Papka R E, “Distribution and origin of corticotropin-releasing factor-immunoreactive axons in the female rat lumbosacral spinal cord.,” NEOMED Bibliography Database, accessed April 20, 2021, https://neomed.omeka.net/items/show/3055.

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