Pathophysiology of empty nose syndrome.

Pathophysiology of empty nose syndrome.

Sozansky Jeanie; Houser Steven M

The Laryngoscope

2015

2015-01

OBJECTIVES/HYPOTHESIS: To review current knowledge on nasal airflow sensation in relation to empty nose syndrome (ENS). STUDY DESIGN: PubMed searches. METHODS: Current literature pertaining to measurement of nasal patency, mechanism of sensory perception of nasal airflow, and ENS. RESULTS: A reliance on pure anatomical analysis of the anatomy in ENS falls short of explaining the disorder. Our understanding of subjective nasal sensation has advanced, as has our understanding of the flow of air through the nose. Neural healing following a surgical insult may not result in a return to a normal physiologic state. Aberrations in neurosensory systems from improper healing may play a major role in the abnormal sensations ENS patients experience. CONCLUSIONS: An evidence-based hypothesis for the development and symptoms of ENS is offered.

Brain – Physiopathology; Brain/physiopathology; Computer Simulation; Dyspnea – Physiopathology; Dyspnea/physiopathology; Empty nose syndrome; Humans; Nasal Mucosa – Innervation; Nasal Mucosa/*innervation; Nasal Obstruction – Physiopathology; Nasal Obstruction/*physiopathology; nasal sensation; Neural Pathways – Physiopathology; Olfactory Pathways/physiopathology; Postoperative Complications – Physiopathology; Postoperative Complications/*physiopathology; Pulmonary Ventilation/*physiology; Respiratory Airflow – Physiology; Sensory Receptor Cells – Physiology; Sensory Receptor Cells/*physiology; Syndrome; Thermoreceptors – Physiopathology; Thermoreceptors/physiopathology; Tomography; Trigeminal Nerve – Physiopathology; Trigeminal Nerve/physiopathology; turbinate surgery; Turbinates – Physiopathology; Turbinates – Surgery; Turbinates/*physiopathology/*surgery; Wound Healing – Physiology; Wound Healing/*physiology; X-Ray Computed

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