The effect of reserpine treatment in vivo upon L-dopa and amphetamine evoked dopamine and DOPAC efflux in vitro from the corpus striatum of male rats.

Title

The effect of reserpine treatment in vivo upon L-dopa and amphetamine evoked dopamine and DOPAC efflux in vitro from the corpus striatum of male rats.

Creator

Dluzen D E; Liu B

Publisher

Journal of neural transmission. General section

Date

1994
1994

Description

In the present experiment we tested the effects of L-DOPA and amphetamine upon dopamine and DOPAC efflux in vitro from superfused corpus striatal tissue fragments of male rats who had been pretreated with reserpine. Male rats were treated with reserpine (5 mg/kg) or its vehicle at 24 hours prior to sacrifice and superfusion of the corpus striatum. Two different modes of L-DOPA (5 microM) and amphetamine (10 microM) stimulation, a brief 10-minute and a continuous

Subject

3; 4-Dihydroxyphenylacetic Acid/*metabolism; Amphetamine/*pharmacology; Animals; Cell Compartmentation; Corpus Striatum/*drug effects/metabolism; Dopamine/*metabolism; Drug Interactions; Levodopa/*pharmacology; Male; Rats; Research Design; Reserpine/*pharmacology; Secretory Rate/drug effects; Sprague-Dawley

Identifier

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

209–222

Issue

3

Volume

95

Citation

Dluzen D E; Liu B, “The effect of reserpine treatment in vivo upon L-dopa and amphetamine evoked dopamine and DOPAC efflux in vitro from the corpus striatum of male rats.,” NEOMED Bibliography Database, accessed September 21, 2021, https://neomed.omeka.net/items/show/3146.

Social Bookmarking