Necrotizing Soft Tissue Infections.

Title

Necrotizing Soft Tissue Infections.

Creator

File Thomas M

Publisher

Current infectious disease reports

Date

2003
2003-10

Description

Necrotizing soft tissue infections are characterized by necrosis of skin and associated structures. Despite advances in the diagnosis and treatment of these infections, the mortality remains high. There have been increasing reports of necrotizing fasciitis caused by group A Streptococcus over the past decade. Recent information supports the role of superantigens in the pathogenesis of this infection. The approach to management requires expeditious evaluation with early surgery and appropriate antimicrobial agents. Limited data suggest that surgical debridement may be delayed in selected patients until the patient is stable by the use of intravenous immunoglobulin, which can neutralize superantigens.

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

407–415

Issue

5

Volume

5

Citation

File Thomas M, “Necrotizing Soft Tissue Infections.,” NEOMED Bibliography Database, accessed March 28, 2024, https://neomed.omeka.net/items/show/3258.