Conditioned place preference produced by the psychostimulant cathinone.

Title

Conditioned place preference produced by the psychostimulant cathinone.

Creator

Schechter M D; Meehan S M

Publisher

European journal of pharmacology

Date

1993
1993-02

Description

Previous work has indicated that the psychostimulant cathinone produces a location preference in the conditioned place preference task. The present study expanded upon this earlier work by examining the dose-response nature of cathinone-induced conditioned place preference, as well as testing its effect upon spontaneous locomotor activity. At doses ranging from 0.2 to 1.6 mg/kg, cathinone produced a conditioned place preference at all but the lowest dose, and the highest dose but not the lowest dose increased locomotor activity. Results are discussed in terms of dopaminergic mediation of conditioned place preference and the relationship between conditioned place preference and locomotion being subserved by the same neuronal system.

Subject

Alkaloids/administration & dosage/*pharmacology; Animals; Central Nervous System Stimulants/administration & dosage/*pharmacology; Choice Behavior/drug effects; Conditioning (Psychology)/drug effects; Dose-Response Relationship; Drug; Habituation; Male; Motor Activity/*drug effects; Psychophysiologic; Rats; Sprague-Dawley

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

135–138

Issue

1

Volume

232

Citation

Schechter M D; Meehan S M, “Conditioned place preference produced by the psychostimulant cathinone.,” NEOMED Bibliography Database, accessed May 8, 2021, https://neomed.omeka.net/items/show/3298.

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