The effects of anticonvulsant drugs on long-term potentiation (LTP) in the rat hippocampus.

The effects of anticonvulsant drugs on long-term potentiation (LTP) in the rat hippocampus.

Lee G Y; Brown L M; Teyler T J

Brain research bulletin

1996

1996

In hippocampal CA1 area, there are at least two forms of long-term potentiation (LTP): one is N-methyl-D-aspartate (NMDA) receptor-dependent LTP (NMDA LTP), which is induced with a 25 Hz tetanus and blocked by 50 microM

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anticonvulsants/*pharmacology; Calcium Channel Blockers/pharmacology; Enzyme Inhibitors/pharmacology; Excitatory Amino Acid Agonists/pharmacology; Female; Hippocampus/*drug effects; Isoquinolines/pharmacology; Long-Term Potentiation/*drug effects; Male; Membrane Potentials/drug effects; N-Methylaspartate/pharmacology; Piperazines/pharmacology; Protein Kinase C/antagonists & inhibitors; Rats; Synapses/drug effects

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

39–42

1

39