Locomotor activity but not conditioned place preference is differentially affected by a moderate dose of ethanol administered to P and NP rats.

Title

Locomotor activity but not conditioned place preference is differentially affected by a moderate dose of ethanol administered to P and NP rats.

Creator

Schechter M D

Publisher

Alcohol (Fayetteville, N.Y.)

Date

1992
1992-06

Description

The conditioned place preference (CPP) test and spontaneous motor activity were used in order to determine if ethanol-preferring (P) rats differ from ethanol nonpreferring (NP) rats after the administration of a moderate (1.0 g/kg) dose of ethanol. Results indicate that both of the selectively bred lines of rats found ethanol aversive, with little difference between the P and the NP rats. In contrast, the NP rats were shown to be more sensitive to the motor-impairing effect of ethanol.

Subject

*Alcohol Drinking; *Environment; Animals; Dose-Response Relationship; Drug; Ethanol/*pharmacology; Male; Motor Activity/*drug effects; Mutant Strains; Rats; Reinforcement (Psychology)

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

185–188

Issue

3

Volume

9

Citation

Schechter M D, “Locomotor activity but not conditioned place preference is differentially affected by a moderate dose of ethanol administered to P and NP rats.,” NEOMED Bibliography Database, accessed May 26, 2022, https://neomed.omeka.net/items/show/3384.

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