The role of transcervical thymectomy in patients with hyperparathyroidism.

Title

The role of transcervical thymectomy in patients with hyperparathyroidism.

Creator

Welch Kellen; McHenry Christopher R

Publisher

American journal of surgery

Date

2012
2012-03

Description

BACKGROUND: The most common location for supernumerary or ectopic parathyroid glands is the thymus. METHODS: A review of patients who underwent parathyroidectomy for hyperparathyroidism from 1990 to 2010 was completed to determine indications for thymectomy, the yield of parathyroid tissue, and outcome of therapy. RESULTS: Seventy of 379 patients with hyperparathyroidism underwent parathyroidectomy and transcervical thymectomy. Intrathymic parathyroid tissue was present in 23 (33%) patients, including supernumerary glands in 8 patients (11%). Indications for thymectomy were renal hyperparathyroidism in 35 patients (50%) and primary hyperparathyroidism with a missing inferior gland in 20 patients (29%), an ectopic adenoma in 9 patients (13%), hyperplasia in 5 patients (7%), and carcinoma in 1 patient (1%). Cure rates were similar (96% and 98%; P = not significant) and only transient hypocalcemia was higher (51% vs 24%, P \textless .05) after parathyroidectomy with thymectomy versus parathyroidectomy alone. CONCLUSIONS: Transcervical thymectomy results in a high yield of parathyroid tissue and is essential for cure of selected patients with hyperparathyroidism.

Subject

*Thymectomy/methods; Adult; Aged; Female; Humans; Hyperparathyroidism/etiology/pathology/*surgery; Hypocalcemia/etiology; Male; Middle Aged; Parathyroidectomy; Postoperative Complications; Retrospective Studies; Thymus Gland/pathology/surgery; Treatment Outcome

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

292–5; discussion 295–296

Issue

3

Volume

203

Citation

Welch Kellen; McHenry Christopher R, “The role of transcervical thymectomy in patients with hyperparathyroidism.,” NEOMED Bibliography Database, accessed May 27, 2022, https://neomed.omeka.net/items/show/3455.

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