Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening.

Title

Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening.

Creator

Geldenhuys Werner J; Darvesh Altaf S; Funk Max O; Van der Schyf Cornelis J; Carroll Richard T

Publisher

Bioorganic & medicinal chemistry letters

Date

2010
2010-09

Description

Parkinson's disease is a severe debilitating neurodegenerative disorder. Recently, it was shown that the peroxisome proliferating-activator receptor-gamma agonist pioglitazone protected mice from

Subject

Models; Molecular; Monoamine Oxidase Inhibitors/chemistry/*pharmacology; Monoamine Oxidase/*drug effects; Structure-Activity Relationship

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

URL Address

http://doi.org/10.1016/j.bmcl.2010.06.128

Pages

5295–5298

Issue

17

Volume

20

Citation

Geldenhuys Werner J; Darvesh Altaf S; Funk Max O; Van der Schyf Cornelis J; Carroll Richard T, “Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening.,” NEOMED Bibliography Database, accessed April 18, 2024, https://neomed.omeka.net/items/show/3492.