Measuring residual activity of topical antimicrobials: is the residual activity of chlorhexidine an artefact of laboratory methods?

Title

Measuring residual activity of topical antimicrobials: is the residual activity of chlorhexidine an artefact of laboratory methods?

Creator

Rutter J D; Angiulo K; Macinga D R

Publisher

The Journal of hospital infection

Date

2014
2014-10

Description

Residual activity of chlorhexidine gluconate (CHG) was evaluated by pretreating hands with CHG and then touching Staphylococcus aureus dried on to stainless steel discs. By this method, no reduction in bacteria was observed up to 15 min, suggesting that residual CHG does not offer protection against contamination with transient micro-organisms in clinical practice.

Subject

Adolescence; Adolescent; Adult; Aged; Anti-Infective Agents; Antiinfective Agents; Artifacts; Chlorhexidine; Chlorhexidine – Analogs and Derivatives; Chlorhexidine – Pharmacodynamics; Chlorhexidine/*analogs & derivatives/pharmacology; Hand Disinfection/methods; Hand hygiene; Handwashing – Methods; Humans; Local – Pharmacodynamics; Local/*pharmacology; Middle Age; Middle Aged; Persistence; Residual activity; Residual kill; Skin – Drug Effects; Skin – Microbiology; Skin/drug effects/*microbiology; Staphylococcus Aureus – Drug Effects; Staphylococcus aureus/*drug effects; Transient bacteria; Young Adult

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

113–115

Issue

2

Volume

88

Citation

Rutter J D; Angiulo K; Macinga D R, “Measuring residual activity of topical antimicrobials: is the residual activity of chlorhexidine an artefact of laboratory methods?,” NEOMED Bibliography Database, accessed April 20, 2021, https://neomed.omeka.net/items/show/3662.

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