The niacin response biomarker as a schizophrenia endophenotype: A status update.

Title

The niacin response biomarker as a schizophrenia endophenotype: A status update.

Creator

Messamore Erik

Publisher

Prostaglandins, leukotrienes, and essential fatty acids

Date

2018
2018-09

Description

Increasingly, it is recognized that the behavioral syndrome of schizophrenia is not a unitary disease with a single underlying cause. Rather, it may have several possible etiologies, and its symptoms may arise from multiple causes. Such heterogeneity could account for some of the difficulties in elucidating its genetics, and may also explain clinical observations of variable medication response in schizophrenia. The ability to categorize schizophrenia using objectively recognizable, physiologically-based subtypes promises to make our understanding of schizophrenia more comprehensive and could provide some clues for more personalized treatment. This paper will review the extent to which an abnormally blunted skin flush response to niacin satisfies the criteria for a schizophrenia endophenotype.

Subject

Biomarker; Endophenotype; Niacin; Schizophrenia; Vasodilation

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

95–97

Volume

136

Citation

Messamore Erik, “The niacin response biomarker as a schizophrenia endophenotype: A status update.,” NEOMED Bibliography Database, accessed May 5, 2021, https://neomed.omeka.net/items/show/3775.

Social Bookmarking