Identification of novel pathways that control farnesoid X receptor-mediated hypocholesterolemia.

Title

Identification of novel pathways that control farnesoid X receptor-mediated hypocholesterolemia.

Creator

Zhang Yanqiao; Yin Liya; Anderson Jody; Ma Huiyan; Gonzalez Frank J; Willson Timothy M; Edwards Peter A

Publisher

The Journal of biological chemistry

Date

2010
2010-01

Description

Farnesoid X receptor (FXR) plays important regulatory roles in bile acid, lipoprotein, and glucose homeostasis. Here, we have utilized Fxr(-/-) mice and mice deficient in scavenger receptor class B type I (SR-BI), together with an

Subject

Absorption; Animals; Biological; Cell Line; Cholesterol/*metabolism; Class B/*genetics/metabolism; Coronary Disease/metabolism; Cytoplasmic and Nuclear/*metabolism; Glucose/metabolism; Hepatocyte Nuclear Factor 4/metabolism; Homeostasis; Humans; Lipoproteins/metabolism; Liver/metabolism; Mice; Models; Receptors; Scavenger Receptors

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

3035–3043

Issue

5

Volume

285

Citation

Zhang Yanqiao; Yin Liya; Anderson Jody; Ma Huiyan; Gonzalez Frank J; Willson Timothy M; Edwards Peter A, “Identification of novel pathways that control farnesoid X receptor-mediated hypocholesterolemia.,” NEOMED Bibliography Database, accessed December 8, 2021, https://neomed.omeka.net/items/show/4062.

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