Identification of novel pathways that control farnesoid X receptor-mediated hypocholesterolemia.
Title
Identification of novel pathways that control farnesoid X receptor-mediated hypocholesterolemia.
Creator
Zhang Yanqiao; Yin Liya; Anderson Jody; Ma Huiyan; Gonzalez Frank J; Willson Timothy M; Edwards Peter A
Publisher
The Journal of biological chemistry
Date
2010
2010-01
Description
Farnesoid X receptor (FXR) plays important regulatory roles in bile acid, lipoprotein, and glucose homeostasis. Here, we have utilized Fxr(-/-) mice and mice deficient in scavenger receptor class B type I (SR-BI), together with an
Subject
Absorption; Animals; Biological; Cell Line; Cholesterol/*metabolism; Class B/*genetics/metabolism; Coronary Disease/metabolism; Cytoplasmic and Nuclear/*metabolism; Glucose/metabolism; Hepatocyte Nuclear Factor 4/metabolism; Homeostasis; Humans; Lipoproteins/metabolism; Liver/metabolism; Mice; Models; Receptors; Scavenger Receptors
Identifier
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Citation
Zhang Yanqiao; Yin Liya; Anderson Jody; Ma Huiyan; Gonzalez Frank J; Willson Timothy M; Edwards Peter A, “Identification of novel pathways that control farnesoid X receptor-mediated hypocholesterolemia.,” NEOMED Bibliography Database, accessed June 22, 2021, https://neomed.omeka.net/items/show/4062.