Lack of bone stiffness/strength contribution to osteoarthritis–evidence for primary role of cartilage damage.

Title

Lack of bone stiffness/strength contribution to osteoarthritis–evidence for primary role of cartilage damage.

Creator

Rothschild B M; Panza R K

Publisher

Rheumatology (Oxford, England)

Date

2007
2007-02

Description

OBJECTIVES: This study was performed to assess osseous contributions to osteoarthritis, obviating the analysis challenges presented by confounding factors in humans and rarity of osteoarthritis in free-ranging mammals. METHODS: Frequency of osteoarthritis in 21 bird species was examined and contrasted with measures of afflicted element bone stiffness and strength and compression/tension-resistant characteristics. RESULTS: Osteoarthritis was present in the ankle of 0-16% of bird species analysed, independent of bone laminarity, cortical thickness, circularity, polarization, cross-sectional diameter, length and pneumatization. CONCLUSIONS: No correlation of frequency of osteoarthritis with parameters of bone strength and biomechanical parameters was found, suggesting that bone is only secondarily affected in osteoarthritis and that cartilage is the initial target of the disease.

Subject

Animal; Animals; Articular/physiopathology; Biomechanical Phenomena; Bird Diseases/*physiopathology; Birds; Bone and Bones/*physiopathology; Cartilage; Disease Models; Mechanical; Osteoarthritis/*physiopathology/*veterinary; Species Specificity; Stress

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

246–249

Issue

2

Volume

46

Citation

Rothschild B M; Panza R K, “Lack of bone stiffness/strength contribution to osteoarthritis–evidence for primary role of cartilage damage.,” NEOMED Bibliography Database, accessed August 4, 2021, https://neomed.omeka.net/items/show/4208.

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