Thermal aspects of the use of polymethylmethacrylate in large metaphyseal defects in bone. A clinical review and laboratory study.

Title

Thermal aspects of the use of polymethylmethacrylate in large metaphyseal defects in bone. A clinical review and laboratory study.

Creator

Leeson M C; Lippitt S B

Publisher

Clinical orthopaedics and related research

Date

1993
1993-10

Description

The potential necrotizing effects of the heat produced by the exothermic polymerization process has raised questions regarding the use of polymethylmethacrylate (PMMA) in orthopedic surgery. An experimental model was used to: (1) analyze the amplitude and distribution of heat in bone taken from autopsy specimens when large metaphyseal defects (simulating tumor excision) were filled with curing PMMA and (2) to observe any significant necrotizing temperatures. The experimental design included two experimental groups of five distal femora into which either a small- or large-bore defect was made in the lateral epicondylar region. These defects were filled with either one or two packs of PMMA cement, and temperature probes were used to record temperature elevations at the cement core, the bone-cement interface, and the surrounding 1-,

Subject

*Hot Temperature; Bone Neoplasms/pathology/*surgery; Cadaver; Humans; Methylmethacrylates/*therapeutic use; Necrosis

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

239–245

Issue

295

Citation

Leeson M C; Lippitt S B, “Thermal aspects of the use of polymethylmethacrylate in large metaphyseal defects in bone. A clinical review and laboratory study.,” NEOMED Bibliography Database, accessed May 16, 2022, https://neomed.omeka.net/items/show/4254.

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