Diagnosis and Treatment of Clostridium difficile Infection (CDI).

Title

Diagnosis and Treatment of Clostridium difficile Infection (CDI).

Creator

Gerding Dale N; File Thomas M Jr; McDonald L Clifford

Publisher

Infectious diseases in clinical practice (Baltimore, Md.)

Date

2016
2016-01

Description

Early and accurate diagnosis is essential for optimal treatment of individuals with Clostridium difficile infection (CDI) and for implementation of effective infection control procedures. The decision about which diagnostic test to use is an important one that should be based on test sensitivity, specificity, and predictive value. The challenges of CDI go beyond rapid identification and management of symptomatic patients. Asymptomatic carriage has long been suspected in C. difficile transmission, but it may play a larger role than previously thought. Emerging information also shows that patients treated for CDI remain colonized for many weeks after symptom resolution. In fact, stool culture positivity increases during the first weeks following treatment completion. Treatments that reduce the duration and degree of asymptomatic shedding could have added benefit for reduced transmission.

Subject

CDI; Clostridium difficile; diagnostic test; treatment

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

3–10

Issue

1

Volume

24

Citation

Gerding Dale N; File Thomas M Jr; McDonald L Clifford, “Diagnosis and Treatment of Clostridium difficile Infection (CDI).,” NEOMED Bibliography Database, accessed December 5, 2021, https://neomed.omeka.net/items/show/4366.

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