The treatment of palmar and plantar warts using natural alpha interferon and a needleless injector.

The treatment of palmar and plantar warts using natural alpha interferon and a needleless injector.

Brodell R T; Bredle D L

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]

1995

1995-03

BACKGROUND: The treatment of palmar and plantar warts is difficult and often frustrating. The need for multiple destructive treatments and recurrences after apparent cure are common. OBJECTIVE: The purpose of this study was to determine if intralesional natural alpha interferon might offer an effective alternative therapy for common plantar and palmar warts. METHODS: A series of 22 private office patients with palmar and plantar warts were treated with intralesional natural alpha interferon using a needless injector. We treated twice weekly for a minimum of 8 weeks or until clear. RESULTS: Sixteen patients (73%) showed complete clearing of their warts in a mean of 11 weeks of twice weekly treatment. Upon follow-up, which averaged 9.5 months, 17 of 21 patients (81%) remained clear of their warts. CONCLUSION: Natural alpha interferon by needless injector appears to represent an effective alternative treatment for palmar and plantar human papillomavirus lesions. Further study of this modality is indicated.

Adolescent; Adult; Child; Female; Foot Dermatoses/*therapy; Hand Dermatoses/*therapy; Humans; Injections; Interferon-alpha/*administration & dosage/therapeutic use; Intralesional; Jet; Male; Middle Aged; Warts/*therapy

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