Angiomatoid fibrous histiocytoma in a six-year-old child.

Title

Angiomatoid fibrous histiocytoma in a six-year-old child.

Creator

Cernik Christina; Channaiah Deepa; Trevino Julian

Publisher

Pediatric dermatology

Date

2009
2009-10

Description

We report a case of AFH presenting as an asymptomatic subcutaneous nodule on the arm of a 6-year-old boy. AFH is a fibrohistiocytic tumor of intermediate malignancy. Predominantly seen in children and young adults, AFH presents as a deep dermal or subcutaneous nodule usually on the extremities. The histology is characterized by a fibrous capsule, surrounding lymphocytic infiltrate and blood-filled cystic spaces lined by flattened tumor cells. AFH cells express desmin, epithelial membrane antigen, and CD 68 in over 60% of cases; they are negative for myogenin, MYOD1, and endothelial markers. Rate of local recurrence is 2% to 20%. The metastatic rate is 1%. Management is with wide surgical excision and careful follow-up.

Subject

Biopsy; Child; Hemangioma/*pathology/surgery; Histiocytoma; Humans; Male; Malignant Fibrous/*pathology/surgery; Skin Neoplasms/*pathology/surgery

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

636–638

Issue

5

Volume

26

Citation

Cernik Christina; Channaiah Deepa; Trevino Julian, “Angiomatoid fibrous histiocytoma in a six-year-old child.,” NEOMED Bibliography Database, accessed May 19, 2022, https://neomed.omeka.net/items/show/4465.

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