Temporal changes in left ventricular function after massive sympathetic nervous system activation.

Title

Temporal changes in left ventricular function after massive sympathetic nervous system activation.

Creator

Lang S A; Maron M B; Bosso F J; Pilati C F

Publisher

Canadian journal of physiology and pharmacology

Date

1994
1994-06

Description

Intense activation of the sympathetic nervous system (SNS) decreases the contractile state of the rabbit left ventricle (LV). In this study, we determined the time course of LV dysfunction after massive central activation of the SNS in dogs. Veratrine (40-80 micrograms/kg) was injected intracisternally to activate the SNS in six chloralose-anesthetized dogs, and LV end-diastolic pressure (LVEDP), cardiac output, heart rate, and aortic pressure (Pa) were measured at

Subject

Acidosis/physiopathology; Anesthesia; Animals; Blood Pressure/physiology; Cardiac Output/physiology; Catecholamines/blood; Dogs; Electron; Female; Heart Rate/physiology; Heart Ventricles/anatomy & histology/ultrastructure; Hypertension/physiopathology; Left/*physiology; Male; Microscopy; Sympathetic Nervous System/drug effects/*physiology; Ventricular Function; Veratrine/pharmacology

Identifier

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

693–700

Issue

6

Volume

72

Citation

Lang S A; Maron M B; Bosso F J; Pilati C F, “Temporal changes in left ventricular function after massive sympathetic nervous system activation.,” NEOMED Bibliography Database, accessed December 1, 2021, https://neomed.omeka.net/items/show/4561.

Social Bookmarking