Intracellular recording reveals temporal integration in inferior colliculus neurons of awake bats.

Title

Intracellular recording reveals temporal integration in inferior colliculus neurons of awake bats.

Creator

Voytenko S V; Galazyuk A V

Publisher

Journal of neurophysiology

Date

2007
2007-02

Description

The central nucleus of the inferior colliculus (IC) is a major integrative center in the central auditory system. It receives information from both the ascending and descending auditory pathways. To determine how single IC neurons integrate information over a wide range of sound frequencies and sound levels, we examined their intracellular responses to frequency-modulated (FM) sounds in awake little brown bats (Myotis lucifugus). Postsynaptic potentials were recorded in response to downward FM sweeps of the range typical for little brown bats (80-20 kHz) and to three FM subcomponents (80-60, 60-40, and 40-20 kHz). The majority of recorded neurons responded to the 80- to 20-kHz downward FM sweep with a complex response. In this response an initial hyperpolarization was followed by depolarization with or without spike followed by hyperpolarization. Intracellular recordings in response to three FM subcomponents revealed that these neurons receive excitatory and inhibitory inputs from a wide range of sound frequencies. One third of IC neurons performed nearly linear temporal summation across a wide range of sound frequencies, whereas two thirds of IC neurons exhibited nonlinear summation with different degrees of nonlinearity. Some IC neurons showed different latencies of postsynaptic potentials in response to different FM subcomponents. Often responses to the later FM subcomponent occurred before responses to the earlier ones. This phenomenon may be responsible for response selectivity of IC neurons to FM sweeps.

Subject

Acoustic Stimulation; Animals; Chiroptera/*physiology; Data Interpretation; Electrophysiology; Excitatory Postsynaptic Potentials/physiology; Inferior Colliculi/cytology/*physiology; Inhibitory Postsynaptic Potentials/physiology; Microelectrodes; Neurons/*physiology; Pitch Perception; Statistical

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

1368–1378

Issue

2

Volume

97

Citation

Voytenko S V; Galazyuk A V, “Intracellular recording reveals temporal integration in inferior colliculus neurons of awake bats.,” NEOMED Bibliography Database, accessed September 23, 2021, https://neomed.omeka.net/items/show/4676.

Social Bookmarking