Treatment of bacteriuria in pregnancy.

Title

Treatment of bacteriuria in pregnancy.

Creator

Tan J S; File T M Jr

Publisher

Drugs

Date

1992
1992-12

Description

The presence of bacteriuria during gestation increases the chance of acute pyelonephritis. Treatment of bacteriuria in pregnancy reduces subsequent development of symptomatic disease. Numerous studies have shown that single-dose therapy for asymptomatic bacteriuria is as effective as longer course of treatment. Single-dose therapy also has the advantages of improved compliance, reduced costs, and less adverse effects resulting from long term therapy. Follow-up cultures following antimicrobial treatment should be used for early detection of recurrence or relapse. If the urine culture yields no growth, a urine culture at a monthly interval will suffice. If on the other hand bacteriuria is present, a repeat course of antimicrobial therapy should be chosen based on antimicrobial susceptibility testing. A longer course of therapy, possibly with a different drug, is recommended for women with a positive follow-up urine culture. Acute cystitis may be treated with the same regimen as asymptomatic bacteriuria. When upper urinary tract infection is suspected, hospitalisation and a longer course of therapy is recommended. If the organism is susceptible to cefalexin or nitrofurantoin, postcoital prophylaxis with either agent for the remainder of the pregnancy may be beneficial.

Subject

Female; Humans; Pregnancy; Pregnancy Complications; Anti-Infective Agents/adverse effects; Bacteriuria/diagnosis/*drug therapy/microbiology; Infectious/diagnosis/*drug therapy/microbiology

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

972–980

Issue

6

Volume

44

Citation

Tan J S; File T M Jr, “Treatment of bacteriuria in pregnancy.,” NEOMED Bibliography Database, accessed October 27, 2021, https://neomed.omeka.net/items/show/5061.

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