Focal ellipsoid deposits in the atrial myocytes of Syrian hamster.

Title

Focal ellipsoid deposits in the atrial myocytes of Syrian hamster.

Creator

Gilloteaux J; Jennes L; Stoeckel M E; Vanderhaeghen J J

Publisher

Ultrastructural pathology

Date

1994
1994-04

Description

A peculiar hyaline sarcoplasmic inclusion in the atrial myocytes of old female Syrian hamsters is described. This type of inclusion resembles that described in rare human cardiomyopathy. They have also been described in other rodents and have been speculated eventually to contain atrial natriuretic factor (ANF). The present study demonstrated that they are fibrillar in nature, however, and do not contain ANF-immunoreactive product. Because their morphologic aspect is analogous to that described in human heart and in the pathology of other contractile tissues, it is suggested that they probably consist of intermediate filaments and/or associated macromolecules.

Subject

Female; Male; Animals; Immunohistochemistry; Cricetinae; Mesocricetus; Heart Atria/metabolism/*ultrastructure; Inclusion Bodies/metabolism/*ultrastructure; Microscopy; Immunoelectron

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

221–227

Issue

1

Volume

18

Citation

Gilloteaux J; Jennes L; Stoeckel M E; Vanderhaeghen J J, “Focal ellipsoid deposits in the atrial myocytes of Syrian hamster.,” NEOMED Bibliography Database, accessed September 26, 2021, https://neomed.omeka.net/items/show/5095.

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