Developmental hearing loss impairs signal detection in noise: putative central mechanisms.

Title

Developmental hearing loss impairs signal detection in noise: putative central mechanisms.

Creator

Gay Jennifer D; Voytenko Sergiy V; Galazyuk Alexander V; Rosen Merri J

Publisher

Frontiers in systems neuroscience

Date

2014
1905-07

Description

Listeners with hearing loss have difficulty processing sounds in noisy environments. This is most noticeable for speech perception, but is reflected in a basic auditory processing task: detecting a tonal signal in a noise background, i.e., simultaneous masking. It is unresolved whether the mechanisms underlying simultaneous masking arise from the auditory periphery or from the central auditory system. Poor detection in listeners with sensorineural hearing loss (SNHL) is attributed to cochlear hair cell damage. However, hearing loss alters neural processing in the central auditory system. Additionally, both psychophysical and neurophysiological data from normally hearing and impaired listeners suggest that there are additional contributions to simultaneous masking that arise centrally. With SNHL, it is difficult to separate peripheral from central contributions to signal detection deficits. We have thus excluded peripheral contributions by using an animal model of early conductive hearing loss (CHL) that provides auditory deprivation but does not induce cochlear damage. When tested as adults, animals raised with CHL had increased thresholds for detecting tones in simultaneous noise. Furthermore, intracellular in vivo recordings in control animals revealed a cortical correlate of simultaneous masking: local cortical processing reduced tone-evoked responses in the presence of noise. This raises the possibility that altered cortical responses which occur with early CHL can influence even simple signal detection in noise.

Subject

masking; auditory cortex; conductive hearing loss; electrophysiology; gerbil; intracellular; noise; signal detection

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

162–162

Volume

8

Citation

Gay Jennifer D; Voytenko Sergiy V; Galazyuk Alexander V; Rosen Merri J, “Developmental hearing loss impairs signal detection in noise: putative central mechanisms.,” NEOMED Bibliography Database, accessed August 3, 2021, https://neomed.omeka.net/items/show/5144.

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