MicroRNAs and lung cancer: Biology and applications in diagnosis and prognosis.

Title

MicroRNAs and lung cancer: Biology and applications in diagnosis and prognosis.

Creator

Mallick Reema; Patnaik Santosh Kumar; Yendamuri Sai

Publisher

Journal of carcinogenesis

Date

2010
2010-08

Description

MicroRNAs are tiny non-coding RNA molecules which play important roles in the epigenetic control of cellular processes by preventing the translation of proteins from messenger RNAs (mRNAs). A single microRNA can target different mRNAs, and an mRNA can be targeted by multiple microRNAs. Such complex interplays underlie many molecular pathways in cells, and specific roles for many microRNAs in physiological as well as pathological phenomena have been identified. Changes in expression of microRNAs have been associated with a wide variety of disease conditions, and microRNA-based biomarkers are being developed for the identification and monitoring of such states. This review provides a general overview of the current state of knowledge about the biology of microRNAs, and specific information about microRNAs with regard to the diagnosis and prognosis of lung cancer.

Subject

gene expression; lung cancer; Carcinogenesis; microRNA

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Citation

Mallick Reema; Patnaik Santosh Kumar; Yendamuri Sai, “MicroRNAs and lung cancer: Biology and applications in diagnosis and prognosis.,” NEOMED Bibliography Database, accessed May 14, 2021, https://neomed.omeka.net/items/show/5215.

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